Outcomes of Implementing in the Real World the Women's Health CoOp Intervention in Cape Town, South Africa.
Outcomes of Implementing in the Real World the Women's Health CoOp Intervention in Cape Town, South Africa.
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DOI：
10.1007/s10461-021-03251-7
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发表时间：
2021-12
影响因子：
4.4
通讯作者：
Zule WA
中科院分区：
文献类型：
--
作者：
Wechsberg WM;Browne FA;Ndirangu J;Bonner CP;Kline TL;Gichane M;Zule WA
南非感染艾滋病毒并饮酒的女性可能无法坚持接受抗逆转录病毒治疗，从而影响该国的 90-90-90 目标。妇女健康合作社 (WHC) 是一项以妇女为中心的艾滋病毒干预措施，在针对南非酗酒和吸毒的重点妇女群体进行的多项试验中显示出有效性。在一项混合实施有效性研究中，医疗保健提供者在常规护理诊所中以改进的阶梯楔形设计实施了 WHC。我们展示了 480 名女性的饮酒和 ART 依从性结果，在 4 个实施周期中 6 个月的随访率为 95%。与第一个周期相比，第四个周期的女性报告酒精使用障碍风险的可能性显着降低（OR = 0.10 [95% CI 0.04, 0.24]），并且在 6 个月随访时报告 ART 依从性的可能性高出 4 倍（OR = 4.16 [95% CI 1.05, 16.51]）。总体而言，可接受性和满意度非常高。 WHC 的干预措施成功地影响了关键女性群体，以减少饮酒并提高 ART 依从性，这对于南非实现 90-90-90 目标至关重要。
Women in South Africa living with HIV who use alcohol may not adhere to ART, affecting the country’s 90-90-90 targets. The Women’s Health CoOp (WHC), a woman-focused HIV intervention, has shown efficacy in numerous trials with key populations of women in South Africa who use alcohol and drugs. In a hybrid implementation effectiveness study, the WHC was implemented in usual care clinics by healthcare providers in a modified stepped-wedge design. We present the outcomes of alcohol use and ART adherence with 480 women, with a 95% 6-month follow-up rate across 4 implementation cycles. Compared with the first cycle, women in the fourth cycle were significantly less likely (OR = 0.10 [95% CI 0.04, 0.24]) to report alcohol use disorder risk and were 4 times more likely (OR = 4.16 [95% CI 1.05, 16.51]) to report ART adherence at 6-month follow-up. Overall, acceptability and satisfaction were extremely high. The WHC intervention was successful in reaching key populations of women to reduce alcohol use and increase ART adherence, which is essential for South Africa to reach the 90-90-90 goals.
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影响因子：
2.2
作者：
Olivier, L.;Curfs, L. M. G.;Viljoen, D. L.
通讯作者：
Viljoen, D. L.
影响因子：
4.2
作者：
Azar, Marwan M.;Springer, Sandra A.;Meyer, Jaimie P.;Altice, Frederick L.
通讯作者：
Altice, Frederick L.
影响因子：
4.2
作者：
Gichane MW;Wechsberg WM;Ndirangu J;Browne FA;Bonner CP;Grimwood A;Shaikh N;Howard B;Zule WA
通讯作者：
Zule WA
影响因子：
2.8
作者：
Howard BN;Van Dorn R;Myers BJ;Zule WA;Browne FA;Carney T;Wechsberg WM
通讯作者：
Wechsberg WM
影响因子：
3.8
作者：
Dunkle, Kristin L.;Jewkes, Rachel K.;Duvvury, Nata
通讯作者：
Duvvury, Nata