Establishment and organization of germ layers in the gastrulating mouse embryo.
Establishment and organization of germ layers in the gastrulating mouse embryo.
复制标题
原肠胚小鼠胚胎胚层的建立和组织。
DOI：
10.1002/9780470514221.ch3
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发表时间：
1992
期刊：
影响因子：
--
通讯作者：
R. Beddington
中科院分区：
文献类型：
--
作者：
P. P. Tam;R. Beddington
通过跟踪小麦胚凝集素-金标记细胞在原条期胚胎中的分布，我们获得了胚胎外胚层细胞在原肠胚形成过程中向定形内胚层和胚胎及胚外中胚层连续募集的直接证据。大多数定形内胚层细胞通过原条的前端进入，并在原肠处最初被纳入中线内胚层，但也有少量内胚层细胞可通过直接从胚胎外胚层分层来招募。预先存在的内脏胚胎内胚层逐渐取代，但不是完全，由新招募的人口殖民的胚胎前肠和脊索。招募的内胚层和细胞的胚胎外胚层和中胚层的晚期原条阶段胚胎的发育命运表明，伴随着建立的胚层，有序的分配预期胎儿组织的特定部位的身体同时发生在所有三个胚层。
By following the distribution of wheat germ agglutinin-gold-labelled cells in primitive streak stage embryos, we obtained direct evidence for a continuous recruitment of the embryonic ectoderm cells to the definitive endoderm and to the embryonic and extraembryonic mesoderm during gastrulation. The majority of the definitive endodermal cells ingressed through the anterior end of the primitive streak and were incorporated initially into the midline endoderm at the archenteron, but a small population of endodermal cells may be recruited by direct delamination from the embryonic ectoderm. The pre-existing visceral embryonic endoderm was progressively replaced, but not totally, by the newly recruited population which colonized the embryonic foregut and the notochord. The developmental fate of the recruited endoderm and that of cells in the embryonic ectoderm and the mesoderm of late primitive streak stage embryos indicate that concomitant with the establishment of the germ layers, an orderly allocation of prospective fetal tissues to specific parts of the body occurs simultaneously in all three germ layers.
影响因子：
4.6
作者：
M. A. Frohman;Monica Boyle;Gail R. Martin
通讯作者：
M. A. Frohman;Monica Boyle;Gail R. Martin
影响因子：
56.9
作者：
BLUMBERG, B;WRIGHT, CVE;CHO, KWY
通讯作者：
CHO, KWY
免疫外科。
影响因子：
2.3
作者：
Achauer,BM;Black,KS;Hewitt,CW;Furnas,DW
通讯作者：
Furnas,DW