Knowledge Domain and Emerging Trends in Ferroptosis Research: A Bibliometric and Knowledge-Map Analysis.

Knowledge Domain and Emerging Trends in Ferroptosis Research: A Bibliometric and Knowledge-Map Analysis.
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铁死亡研究的知识领域和新兴趋势:文献计量和知识图谱分析

DOI:
10.3389/fonc.2021.686726
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发表时间:
2021
影响因子:
4.7
通讯作者:
Xu H
Xu H
中科院分区:
医学3区
文献类型:
--
作者:
Zhang J;Song L;Xu L;Fan Y;Wang T;Tian W;Ju J;Xu H

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确定作者,国家,机构和期刊的合作和影响,评估知识库,发现热点趋势,并检测有关铁凋亡研究的新兴主题。与铁凋亡相关的文章和评论于2020年11月1日从Web of Science Core Collection获得。两个科学计量软件(CiteSpace 5.7和VOSviewer 1.6.15)进行文献计量学和知识地图分析。共有来自61个国家/地区的438个机构的6,867名作者在466种学术期刊上发表了1,267篇论文。与铁中毒相关的出版物迅速增加。Cell Death & Disease发表的关于铁凋亡的论文最多,而Cell是最高的共同被引期刊,出版期刊和共同被引期刊主要在分子和生物学领域。美国和中国是最多产的国家;同时,匹兹堡大学、哥伦比亚大学和广州医科大学是最活跃的机构。布伦特R Stockwell发表的论文最多,而斯科特J狄克逊有最多的共同引用;同时,积极的合作存在于ferroptosis的研究人员。10篇关于综述、机制和疾病的参考文献被视为知识库。铁凋亡研究的五个主要方面包括调节机制、神经系统损伤、癌症、与其他类型细胞死亡的关系以及脂质过氧化。最新的研究热点是纳米粒子、肿瘤治疗、铁代谢及其深入机制。值得注意的是,Nrf 2可能具有转折意义。目前铁凋亡研究的热点是进一步研究其分子机制,以及利用先进的科学技术使铁凋亡相关疾病得到更广泛的应用。本研究采用文献计量学和可视化方法对铁性睑下垂的研究进行了全面的综述。本文的研究结果可为铁性睑下垂的研究提供有益的参考。
To identify the cooperation and impact of authors, countries, institutions, and journals, evaluate the knowledge base, find the hotspot trends, and detect the emerging topics regarding ferroptosis research. The articles and reviews related to ferroptosis were obtained from the Web of Science Core Collection on November 1, 2020. Two scientometric software (CiteSpace 5.7 and VOSviewer 1.6.15) were used to perform bibliometric and knowledge-map analysis. A total of 1,267 papers were included, in 466 academic journals by 6,867 authors in 438 institutions from 61 countries/regions. The ferroptosis-related publications were increasing rapidly. Cell Death & Disease published the most papers on ferroptosis, while Cell was the top co-cited journal, publication journals and co-cited journals were major in the molecular and biology fields. The United States and China were the most productive countries; meanwhile, the University of Pittsburgh, Columbia University and Guangzhou Medical University were the most active institutions. Brent R Stockwell published the most papers, while Scott J Dixon had the most co-citations; simultaneously, active cooperation existed in ferroptosis researchers. Ten references on reviews, mechanisms, and diseases were regarded as the knowledge base. Five main aspects of ferroptosis research included regulation mechanisms, nervous system injury, cancer, relationships with other types of cell death, and lipid peroxidation. The latest hotspots were nanoparticle, cancer therapy, iron metabolism, and in-depth mechanism. Notably Nrf2 might have turning significance. The emerging topics on ferroptosis research were the further molecular mechanism of ferroptosis and the wider application of ferroptosis-related disease with advanced technology. This study performed a full overview of the ferroptosis research using bibliometric and visual methods. The information would provide helpful references for scholars focusing on ferroptosis.
ACSL4 通过塑造细胞脂质成分来决定铁死亡敏感性。
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