Is time-restricted eating (8/16) beneficial for body weight and metabolism of obese and overweight adults? A systematic review and meta-analysis of randomized controlled trials.
Is time-restricted eating (8/16) beneficial for body weight and metabolism of obese and overweight adults? A systematic review and meta-analysis of randomized controlled trials.
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时间限制的饮食（8/16）对肥胖和超重成年人的体重和代谢有益吗？对随机对照试验的系统综述和荟萃分析。
DOI：
10.1002/fsn3.3194
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发表时间：
2023-03
影响因子：
3.9
通讯作者：
中科院分区：
文献类型：
--
作者：
限时饮食（TRE）是一种新的治疗策略，用于管理体重减轻和代谢异常疾病。目前，TRE （8/ 16,8 h进食：16 h禁食）是最常见的TRE形式。因此，本荟萃分析纳入了超重和肥胖成人中TRE（8/16）的随机对照试验（rct），以确定其对体重和代谢的影响。从PubMed、Ovid MEDLINE、Embase和Cochrane Central Register检索了超重和肥胖成人中比较TRE（8/16）与非TRE的相关随机对照试验。本荟萃分析纳入了8项随机对照试验。接受TRE（8/16）治疗的参与者显示出显著的体重减轻（平均差[MD]: - 1.48 kg， 95%可信区间[CI]: - 2.53至- 0.44）和脂肪量减少（MD: - 1.09 kg, 95% CI: - 1.55至- 0.63）。TRE干预组的瘦质量变化无显著差异（MD: - 0.48 kg, 95% CI: - 1.02 ~ 0.05, p = 0.08, i2 = 41%）。能量限制组和早期TRE （eTRE）亚组导致更大的体重减轻。TRE（8/16）对胰岛素抵抗的稳态模型评估有益（HOMA‐IR, MD: - 0.32, 95% CI: - 0.59至- 0.06），但对葡萄糖代谢和脂质谱的其他参数无显著影响。综上所述，TRE(8/16)，特别是eTRE，或与热量摄入限制相结合，是控制超重和肥胖成人体重的潜在治疗策略。TRE（8/16）也降低了HOMA‐IR；因此，它可能对葡萄糖代谢有积极作用。经过分析，我们认为限时饮食（TRE,8/16）是控制超重和肥胖成人体重的潜在治疗策略，特别是老年人和不经常运动的人，而限时饮食可能是减肥的更好选择。TRE（8/16）也能降低HOMA‐IR，因此它可能对葡萄糖代谢有积极作用。本综述旨在评估限时饮食（8/16）对超重和肥胖成人体重和代谢的影响。到2022年5月，进行了荟萃分析和系统评价。
Time‐restricted eating (TRE) is a new therapeutic strategy for the management of weight loss and dysmetabolic diseases. At present, TRE (8/16, 8 h eating:16 h fasting) is the most common form of TRE. Therefore, this meta‐analysis included randomized controlled trials (RCTs) on TRE (8/16) in overweight and obese adults to determine its impact on body weight and metabolism. Articles reviewed from PubMed, Ovid MEDLINE, Embase, and Cochrane Central Register for the relevant RCTs that compared TRE (8/16) to non‐TRE in overweight and obese adults. Eight RCTs were included in this meta‐analysis. Participants following TRE (8/16) showed significant body weight reduction (mean difference [MD]: −1.48 kg, 95% confidence interval [CI]: −2.53 to −0.44) and fat mass reduction (MD: −1.09 kg, 95% CI: −1.55 to −0.63). There was no significant difference in lean mass change with TRE intervention (MD: −0.48 kg, 95% CI: −1.02 to 0.05, p = .08, I 2 = 41%). The energy restriction and early TRE (eTRE) subgroups resulted in greater weight loss. TRE (8/16) showed beneficial effects on the homeostatic model assessment of insulin resistance (HOMA‐IR, MD: −0.32, 95% CI: −0.59 to −0.06), but had no significant effect on other parameters of glucose metabolism and lipid profiles. In conclusion, TRE (8/16), especially eTRE, or in combination with caloric intake restriction, is a potential therapeutic strategy for weight control in overweight and obese adults. TRE (8/16) also reduced HOMA‐IR; therefore, it may have a positive effect on glucose metabolism. After analysis, We believe Time‐restricted eating (TRE,8/16) is a potential therapeutic strategy for controlling weight in adults with overweight and obesity, especially the elderly and people who do not exercise regularly, and eTRE maybe the better choice for weight loss. TRE (8/16) also reduces HOMA‐IR, so maybe it has a positive effect on glucose metabolism. This review aimed to assess the time‐restricted eating (8/16) on body weight and metabolism in overweight and obese adults. A meta‐analysis and systematic review was conducted up to May 2022.
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DOI：
10.3945/ajcn.115.122044
发表时间：
2016-03
期刊：
The American journal of clinical nutrition
影响因子：
--
作者：
Chowdhury EA;Richardson JD;Holman GD;Tsintzas K;Thompson D;Betts JA
通讯作者：
Betts JA
影响因子：
29
作者：
Hatori M;Vollmers C;Zarrinpar A;DiTacchio L;Bushong EA;Gill S;Leblanc M;Chaix A;Joens M;Fitzpatrick JA;Ellisman MH;Panda S
通讯作者：
Panda S
DOI：
10.3390/ijerph17114138
发表时间：
2020-06-01
影响因子：
--
作者：
Domaszewski, Przemyslaw;Konieczny, Mariusz;Sadowska-Krepa, Ewa
通讯作者：
Sadowska-Krepa, Ewa
DOI：
10.1016/0197-2456(86)90046-2
发表时间：
1986-09-01
期刊：
CONTROLLED CLINICAL TRIALS
影响因子：
--
作者：
DERSIMONIAN, R;LAIRD, N
通讯作者：
LAIRD, N
影响因子：
0.9
作者：
Akcoltekin, Alpturk;Engin, Ali Osman;Sevgin, Hikmet
通讯作者：
Sevgin, Hikmet