Sexual functioning in young adult survivors of childhood cancer.
Sexual functioning in young adult survivors of childhood cancer.
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DOI：
10.1002/pon.1641
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发表时间：
2010-08
期刊：
影响因子：
3.6
通讯作者：
Leonard, Marcia
中科院分区：
文献类型：
--
作者：
Zebrack, Brad J.;Foley, Sallie;Wittmann, Daniela;Leonard, Marcia
对儿童癌症幸存者的性行为或性行为的研究倾向于检查发育里程碑的关系或成就，而不是对癌症或治疗的生理反应。本研究的目的是（1）确定儿童癌症幸存者性功能障碍的患病率和风险因素，（2）检查性功能障碍与健康相关生活质量（HRQOL）和心理社会结果的相关程度。599名18-39岁的幸存者完成了性功能、HRQOL、心理困扰和生活满意度的标准化测量。描述性统计评估性症状的患病率。双变量分析确定了性症状的相关性，并检查了症状与HRQOL/心理社会结局之间的相关性。大多数幸存者似乎都做得很好，尽管52%的女性幸存者和32%的男性幸存者报告在一个或多个性功能领域至少有“一点问题”。女性的平均症状评分是男性的两倍多。性症状与报告的健康问题有关。性功能和HRQOL结果之间的显着关联进行了观察，与关联强度的性别差异表明，男性发现性症状比女性更令人痛苦。虽然大多数幸存者似乎在这个重要的生活领域做得很好，但一些年轻的成年幸存者报告了性问题。虽然女性幸存者可能比男性幸存者报告更多的性症状，但男性可能会经历更多与性困难相关的痛苦。需要对这一年轻成人群体的性功能、行为和结果进行更好的具体测量。
Studies of sexuality or sexual behavior in childhood cancer survivors tend to examine relationships or achievement of developmental milestones but not physiological response to cancer or treatment. The purpose of this study is to (1) identify prevalence and risk factors for sexual dysfunction in childhood cancer survivors, and (2) examine the extent to which sexual dysfunction may be associated with health-related quality of life (HRQOL) and psychosocial outcomes. Five hundred ninety-nine survivors age 18-39 years completed standardized measures of sexual functioning, HRQOL, psychological distress and life satisfaction. Descriptive statistics assessed prevalence of sexual symptoms. Bivariate analyses identified correlates of sexual symptoms and examined associations between symptoms and HRQOL/psychosocial outcomes. Most survivors appear to be doing well, although 52% of female survivors and 32% of male survivors reported at least “a little of a problem” in one or more areas of sexual functioning. Mean symptom score for females was more than twice that of males. Sexual symptoms were associated with reporting health problems. Significant associations between sexual functioning and HRQOL outcomes were observed, with gender differences in strengths of association suggesting that males find sexual symptoms more distressing than do females. While most survivors appear to be doing well in this important life domain, some young adult survivors report sexual concerns. While female survivors may report more sexual symptoms than male survivors, males may experience more distress associated with sexual difficulties. Better specified measures of sexual function, behavior and outcomes are needed for this young adult population.
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