Integration of Visual Information in Auditory Cortex Promotes Auditory Scene Analysis through Multisensory Binding.
Integration of Visual Information in Auditory Cortex Promotes Auditory Scene Analysis through Multisensory Binding.
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视觉信息在听觉皮层的整合通过多感觉结合促进听觉场景分析。
DOI：
10.1016/j.neuron.2017.12.034
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发表时间：
2018-02-07
期刊：
影响因子：
16.2
通讯作者：
Bizley JK
中科院分区：
文献类型：
--
作者：
Atilgan H;Town SM;Wood KC;Jones GP;Maddox RK;Lee AKC;Bizley JK
视听信号在大脑中是如何以及在哪里产生多模态对象的，这一点仍然是未知的。一种假设是，动态多感官信号之间的时间相干性提供了一种机制，跨感官形式绑定刺激功能。在这里，我们报告说，当视觉刺激的亮度是时间相干的振幅波动的一个声音的混合物，该声音的代表性增强听觉皮层。重要的是，这种增强扩展到包括声音的约束力和非约束力特征。我们证明，视觉信息传达的视觉皮层通过当地的场电位的相位与听觉皮层内的听觉信息相结合。这些数据提供的证据表明，早期的跨感觉绑定提供了一个自下而上的机制，形成跨感觉对象和多感觉绑定在听觉皮层的作用之一是支持听觉场景分析。视觉刺激可以塑造听觉皮层神经元对声音混合物的反应感觉之间的时间相干性增强了绑定多感觉对象的声音特征视觉刺激引起听觉皮层局部场电位相位的变化视觉诱导的相位效应在视觉皮层可逆性沉默时丢失Atilgan et al.表明听觉和视觉刺激之间的时间相干性塑造了听觉皮层中声音场景的表征。听觉皮层被认为是多感觉结合的场所，视觉皮层的输入支持这些效应。
How and where in the brain audio-visual signals are bound to create multimodal objects remains unknown. One hypothesis is that temporal coherence between dynamic multisensory signals provides a mechanism for binding stimulus features across sensory modalities. Here, we report that when the luminance of a visual stimulus is temporally coherent with the amplitude fluctuations of one sound in a mixture, the representation of that sound is enhanced in auditory cortex. Critically, this enhancement extends to include both binding and non-binding features of the sound. We demonstrate that visual information conveyed from visual cortex via the phase of the local field potential is combined with auditory information within auditory cortex. These data provide evidence that early cross-sensory binding provides a bottom-up mechanism for the formation of cross-sensory objects and that one role for multisensory binding in auditory cortex is to support auditory scene analysis. Visual stimuli can shape how auditory cortical neurons respond to sound mixtures Temporal coherence between senses enhances sound features of a bound multisensory object Visual stimuli elicit changes in the phase of the local field potential in auditory cortex Vision-induced phase effects are lost when visual cortex is reversibly silenced Atilgan et al. demonstrate that temporal coherence between auditory and visual stimuli shapes the representation of a sound scene in auditory cortex. Auditory cortex is identified as a site of multisensory binding, with inputs from visual cortex underpinning these effects.
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DOI：
10.1121/1.4768798
发表时间：
2013-01
期刊：
The Journal of the Acoustical Society of America
影响因子：
--
作者：
Bizley JK;Walker KM;King AJ;Schnupp JW
通讯作者：
Schnupp JW
影响因子：
15.9
作者：
Bizley JK;Maddox RK;Lee AKC
通讯作者：
Lee AKC
影响因子：
4.3
作者：
Chandrasekaran C;Trubanova A;Stillittano S;Caplier A;Ghazanfar AA
通讯作者：
Ghazanfar AA
DOI：
10.1093/cercor/bhl128
发表时间：
2007-09
期刊：
Cerebral cortex (New York, N.Y. : 1991)
影响因子：
--
作者：
Bizley JK;Nodal FR;Bajo VM;Nelken I;King AJ
通讯作者：
King AJ
影响因子：
3.8
作者：
Denison, Rachel N.;Driver, Jon;Ruff, Christian C.
通讯作者：
Ruff, Christian C.