Racial differences in red blood cell transfusion in hospitalized patients with anemia.
Racial differences in red blood cell transfusion in hospitalized patients with anemia.
复制标题
DOI：
10.1111/trf.16935
复制
发表时间：
2022-08
期刊：
影响因子：
2.9
通讯作者：
Meltzer, David
中科院分区：
文献类型：
--
作者：
Prochaska, Micah;Salcedo, Jorge;Berry, Grace;Meltzer, David
当住院患者的血红蛋白 (Hb) 降至限制性输血阈值（7 或 8 g）以下时，指南建议输注红细胞 (RBC)。医院已实施输血政策，以鼓励遵守指南并减少输血实践的差异。然而，输血实践仍然存在差异。本研究的目的是检查患者种族之间接受输血是否存在差异。患有贫血的住院普通内科患者 (Hb < 10 g/dL) 符合资格。卡方检验用于比较按种族总体和最低 Hb 水平内接受输血的患者百分比。使用线性回归来测试患者的种族、最低血红蛋白、接受红细胞输血和输血单位数之间的关联。 4951 名患者同意，其中 1363 名（28%）接受了输血。 71% 的患者是非裔美国人，25% 是白人，4% 是其他种族。总体而言，与白人相比，非裔美国人接受输血的可能性较小（25% vs. 30%，p< .01），并且在 Hb 层内低于 9 g/dL 最低 Hb（Hb 8.0–8.9 g/dL 1% vs. 7%，p < .01；7.0–7.9 g/dL 15% vs. 28%， p < .01；<7 g/dL 80% 与 86%，p < .01）。与白人相比，非洲裔美国人总体上获得的红细胞单位较少 (β = −.17, p < .01)，血红蛋白水平也较低 (β = .14, p < .01)。患者输血时的血红蛋白水平和住院期间接受的红细胞单位总数因患者种族而异。 请参阅本期第 1471–1476 页的社论
Guidelines recommend transfusion of red blood cells (RBC's) when a hospitalized patient's hemoglobin (Hb) drops below a restrictive transfusion threshold, either at 7 or 8 g. Hospitals have implemented transfusion policies to encourage compliance with guidelines and reduce variation in transfusion practice. However, variation in transfusion practice remains. The purpose of this study was to examine whether there is variation in the receipt of transfusion by patient race. Hospitalized general medicine patients with anemia (Hb < 10 g/dL) were eligible. Chi‐squared tests were used to compare the percent of patients receiving a transfusion by race overall and within strata of their nadir Hb. Linear regression was used to test the association between a patient's race, their nadir Hb, receipt of an RBC transfusion, and the number of units transfused. Four thousand nine hundred and fifty‐one patients consented, including 1363 (28%) who received a transfusion. 71% of patients were African American, 25% were White, and 4% were Other Race. Overall African Americans were less likely to be transfused compared to Whites (25% vs. 30%, p < .01), and within Hb strata below a Nadir Hb of 9 g/dL (Hb 8.0–8.9 g/dL 1% vs. 7%, p < .01; 7.0–7.9 g/dL 15% vs. 28%, p < .01; <7 g/dL 80% vs. 86%, p < .01). African Americans also received fewer units of RBC's (β = −.17, p < .01) overall and at lower Hb levels (β = .14, p < .01) compared to Whites. The Hb level at which patients are transfused at and the total number of RBC units received during hospitalization differ by patient race. See editorial on page 1471–1476, in this issue
登录
查看更多内容
影响因子：
120.7
作者：
Bennett-Guerrero, Elliott;Zhao, Yue;Song, Howard K.
通讯作者：
Song, Howard K.
影响因子：
120.7
作者：
Hajjar, Ludhmila A.;Vincent, Jean-Louis;Auler, Jose O. C., Jr.
通讯作者：
Auler, Jose O. C., Jr.
影响因子：
39.2
作者：
Carson, Jeffrey L.;Grossman, Brenda J.;Djulbegovic, Benjamin
通讯作者：
Djulbegovic, Benjamin
影响因子：
9
作者：
Abdelsattar, Zaid M.;Hendren, Samantha;Henke, Peter
通讯作者：
Henke, Peter
影响因子：
2.9
作者：
Chan, Ka Lok Luke;Mak, Wai Man Vivien;Lee, Kwok Kuen Harold
通讯作者：
Lee, Kwok Kuen Harold