Improvement of heart function in postinfarct heart failure swine models after hepatocyte growth factor gene transfer: comparison of low-, medium- and high-dose groups

Improvement of heart function in postinfarct heart failure swine models after hepatocyte growth factor gene transfer: comparison of low-, medium- and high-dose groups
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肝细胞生长因子基因转移后梗死后心力衰竭猪模型心功能的改善:低、中、高剂量组的比较

DOI:
10.1007/s11033-009-9665-5
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发表时间:
2010-04
影响因子:
2.8
通讯作者:
Ma, Wen-zhu
Ma, Wen-zhu
中科院分区:
生物学4区
文献类型:
--
作者:
Li, Chun-jian;Wang, Hui;Cao, Ke-jiang;Ma, Wen-zhu

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尽管在手术和再灌注治疗方面取得了进展,但目前还没有有效的治疗方法来防止心肌梗死后心脏功能的进行性下降。肝细胞生长因子具有强效的血管生成和抗凋亡作用,
Despite advances in surgical and reperfusion therapy, there is no effective therapy currently exists to prevent the progressive decline in cardiac function following myocardial infarction. Hepatocyte growth factor has potent angiogenic and anti-apoptotic
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