Systematic review and meta-analyses of randomized controlled trials examining tinnitus management.
Systematic review and meta-analyses of randomized controlled trials examining tinnitus management.
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DOI：
10.1002/lary.21825
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发表时间：
2011-07
期刊：
影响因子：
2.6
通讯作者：
Hall, Deborah A.
中科院分区：
文献类型：
--
作者：
Hoare, Derek J.;Kowalkowski, Victoria L.;Kang, Sujin;Hall, Deborah A.
关键词：
评估英国卫生部良好实践指南中确定的耳鸣管理策略的现有证据水平。同行评议文献和荟萃分析的系统综述。检索PubMed、剑桥科学文摘、Web of Science和EMBASE(最早至2010年8月)，并于2010年10月手工检索。只有使用有效的症状问卷测量(即，耳鸣痛苦、焦虑、抑郁的测量)的随机对照试验被纳入。28个随机对照试验符合我们的纳入标准，其中大多数为他们报告的效果提供了中等水平的证据。在这些研究中，证据水平通常受到缺乏盲目性、缺乏力量计算以及数据报告不完整的限制。只有检查认知行为疗法的研究数量众多，而且足够相似，才能进行荟萃分析，从这些研究中，认知行为疗法(中等效应大小)的疗效似乎得到了合理的确立。抗抑郁药是唯一一类显示出潜在益处的药物。大多数对耳鸣有益的干预措施的有效性仍有待最终证实。特别是，需要对实践中最常用的干预措施--助听器、面罩和耳鸣再训练疗法--的益处进行高级别评估。
To evaluate the existing level of evidence for tinnitus management strategies identified in the UK Department of Health's Good Practice Guideline. Systematic review of peer-reviewed literature and meta-analyses. Searches were conducted in PubMed, Cambridge Scientific Abstracts, Web of Science, and EMBASE (earliest to August 2010), supplemented by hand searches in October 2010. Only randomized controlled trials that used validated questionnaire measures of symptoms (i.e., measures of tinnitus distress, anxiety, depression) were included. Twenty-eight randomized controlled trials met our inclusion criteria, most of which provide moderate levels of evidence for the effects they reported. Levels of evidence were generally limited by the lack of blinding, lack of power calculations, and incomplete data reporting in these studies. Only studies examining cognitive behavioral therapy were numerous and similar enough to perform meta-analysis, from which the efficacy of cognitive behavioral therapy (moderate effect size) appears to be reasonably established. Antidepressants were the only drug class to show any evidence of potential benefit. The efficacy of most interventions for tinnitus benefit remains to be demonstrated conclusively. In particular, high-level assessment of the benefit derived from those interventions most commonly used in practice, namely hearing aids, maskers, and tinnitus retraining therapy needs to be performed.
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影响因子：
1.9
作者：
Duval, S;Tweedie, R
通讯作者：
Tweedie, R
影响因子：
0.9
作者：
Greimel, KV;Leibetseder, M;Albegger, K
通讯作者：
Albegger, K
影响因子：
3.8
作者：
Beck, AT;Steer, RA;Kabat, M
通讯作者：
Kabat, M
DOI：
10.1111/j.2044-8341.1959.tb00467.x
发表时间：
1959-01-01
期刊：
BRITISH JOURNAL OF MEDICAL PSYCHOLOGY
影响因子：
--
作者：
HAMILTON, M
通讯作者：
HAMILTON, M
影响因子：
3.4
作者：
Folmer, RL;Griest, SE;Martin, WH
通讯作者：
Martin, WH