A semiparametric instrumental variable approach to optimal treatment regimes under endogeneity.
A semiparametric instrumental variable approach to optimal treatment regimes under endogeneity.
复制标题
DOI:
10.1080/01621459.2020.1783272
复制
发表时间:
2021
影响因子:
3.7
通讯作者:
Tchetgen ET
中科院分区:
文献类型:
--
作者:
Cui Y;Tchetgen ET
There is a fast-growing literature on estimating optimal treatment regimes based on randomized trials or observational studies under a key identifying condition of no unmeasured confounding. Because confounding by unmeasured factors cannot generally be ruled out with certainty in observational studies or randomized trials subject to noncompliance, we propose a general instrumental variable approach to learning optimal treatment regimes under endogeneity. Specifically, we establish identification of both value function for a given regime D and optimal regimes with the aid of a binary instrumental variable, when no unmeasured confounding fails to hold. We also construct novel multiply robust classification-based estimators. Furthermore, we propose to identify and estimate optimal treatment regimes among those who would comply to the assigned treatment under a monotonicity assumption. In this latter case, we establish the somewhat surprising result that complier optimal regimes can be consistently estimated without directly collecting compliance information and therefore without the complier average treatment effect itself being identified. Our approach is illustrated via extensive simulation studies and a data application on the effect of child rearing on labor participation.
登录
查看更多内容
影响因子:
4.5
作者:
Athey, Susan;Tibshirani, Julie;Wager, Stefan
通讯作者:
Wager, Stefan
影响因子:
3.7
作者:
Luckett DJ;Laber EB;Kahkoska AR;Maahs DM;Mayer-Davis E;Kosorok MR
通讯作者:
Kosorok MR
影响因子:
3.7
作者:
Angrist, JD;Imbens, GW;Rubin, DB
通讯作者:
Rubin, DB
DOI:
10.1080/01621459.2016.1155993
发表时间:
2017-06-01
影响因子:
3.7
作者:
Linn, Kristin A.;Laber, Eric B.;Stefanski, Leonard A.
通讯作者:
Stefanski, Leonard A.
影响因子:
7.7
作者:
Greenland, S
通讯作者:
Greenland, S