Alpha-tocopherol-based microemulsion improving the stability of carnosic acid and its electrochemical analysis of antioxidant activity
Alpha-tocopherol-based microemulsion improving the stability of carnosic acid and its electrochemical analysis of antioxidant activity
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基于α-生育酚的微乳液提高鼠尾草酸的稳定性及其抗氧化活性的电化学分析
DOI：
10.1016/j.colsurfa.2019.123708
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发表时间：
2019-11
期刊：
影响因子：
--
通讯作者：
Yu Shujuan
中科院分区：
文献类型：
--
作者：
Lei Caiyu;Tang Xiangyi;Chen Mingshun;Chen Hualei;Yu Shujuan
为提高鼠尾草酸（CA）的理化稳定性和水溶性，以吐温20（22.5%）、卵磷脂（4.5%）、丙二醇（9%）、α-生育酚（4%）和去离子水（60%）为原料，制备了鼠尾草酸微乳。ME显示出优异的储存、稀释、热稳定性和光稳定性。同时，所有的ME都具有相对较低的牛顿粘度，并在较宽的剪切速率范围内表现出牛顿行为，表明ME是不连续的。此外，采用电化学方法对微电解质的抗氧化活性进行了评价，结果表明计时电流法用于评价非连续微电解质的抗氧化活性是可行的。计时电流法表明，CA和α-生育酚在ME体系中具有协同抗氧化作用。因此，开发的CA-ME可能是食品工业保护生物活性成分的潜力。
To improve the physicochemical stability and aqueous solubility of carnosic acid (CA), a CA dissolved microemulsion (CA-ME) consisting of Tween 20 (22.5%), lecithin (4.5%), propylene glycol (PG, 9%), α-tocopherol (4%) and diwater (60%) was developed. The ME showed excellent storage, dilution, thermo- and photo-stability. Meanwhile, all the MEs had relatively low Newtonian viscosities and exhibited Newtonian behaviors over a wider range of shear rates, indicating that the MEs were discontinuous. Furthermore, an electrochemical method was used to evaluate the antioxidant activity of the MEs, the results indicated that chronoamperometry was feasible for discontinuous MEs to evaluate their antioxidant activity. In chronoamperometry, CA and α-tocopherol exhibited synergistic antioxidative effect in the ME system. Therefore, the CA-MEs developed here could be a potential for food industry to protect bioactive components.
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