Role of biomechanics and muscle activation strategy in the production of endpoint force patterns in the cat hindlimb.
Role of biomechanics and muscle activation strategy in the production of endpoint force patterns in the cat hindlimb.
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生物力学和肌肉激活策略在猫后肢产生端点力模式中的作用。
DOI：
10.1016/j.jbiomech.2007.06.021
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发表时间：
2007
影响因子：
2.4
通讯作者：
Grill,WarrenM
中科院分区：
文献类型：
--
作者：
Lemay,MichelA;Bhowmik-Stoker,Manoshi;McConnell,GeorgeC;Grill,WarrenM
我们使用了猫后肢的肌肉骨骼模型，比较了三种不同肌肉激活规则下12块后肢肌肉的所有可能组合所产生的端点力的模式：基于统一激活水平的均匀肌肉激活，基于统一（标准化）力产生的均匀肌肉激活，以及基于脊髓运动神经元池地形的激活。力的模式进行了比较与实验获得的模式，在脊髓完整的猫的腰髓微刺激。力模式的大小和方向进行了比较，以及所发现的类型的比例，和表现出零力点（平衡点）的模式的比例。与均匀的激活和运动神经元地形模型得到的力模式是非常相似的实验测量，与差异较大的模式从归一化端点力模型。三种模型之间的力模式和实验结果的类型的比例的差异是显着的每一个模型。均相激活和归一化端点力模型产生的平衡点比例与实验结果相似。结果表明，肌肉生物力学发挥了重要的作用，在限制端点力模式类型的数量，并在类似的水平激活的肌肉组合再现最好的实验结果与椎管内微刺激。
We used a musculoskeletal model of the cat hindlimb to compare the patterns of endpoint forces generated by all possible combination of 12 hindlimb muscles under three different muscle activation rules: homogeneous activation of muscles based on uniform activation levels, homogeneous activation of muscles based on uniform (normalized) force production, and activation based on the topography of spinal motoneuron pools. Force patterns were compared with the patterns obtained experimentally by microstimulation of the lumbar spinal cord in spinal intact cats. Magnitude and orientation of the force patterns were compared, as well as the proportion of the types found, and the proportions of patterns exhibiting points of zero force (equilibrium points). The force patterns obtained with the homogenous activation and motoneuron topography models were quite similar to those measured experimentally, with the differences being larger for the patterns from the normalized endpoint forces model. Differences in the proportions of types of force patterns between the three models and the experimental results were significant for each model. Both homogeneous activation and normalized endpoint force models produced similar proportions of equilibrium points as found experimentally. The results suggest that muscle biomechanics play an important role in limiting the number of endpoint force pattern types, and that muscle combinations activated at similar levels reproduced best the experimental results obtained with intraspinal microstimulation.
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脊髓感觉运动转化：皮肤体位与反射网络之间的关系
DOI：
10.1523/jneurosci.22-18-08170.2002
发表时间：
2002
期刊：
The Journal of Neuroscience
影响因子：
--
作者：
A. Levinsson;H. Holmberg;J. Broman;Mengliang Zhang;J. Schouenborg
通讯作者：
J. Schouenborg
DOI：
10.1109/tnsre.2003.823268
发表时间：
2004-03-01
影响因子：
4.9
作者：
Aoyagi, Y;Mushahwar, VK;Prochazka, A
通讯作者：
Prochazka, A
影响因子：
2.5
作者：
Ting, LH;Macpherson, JM
通讯作者：
Macpherson, JM
影响因子：
2.5
作者：
Lemay, MA;Grill, WM
通讯作者：
Grill, WM
DOI：
10.1073/pnas.0500199102
发表时间：
2005-02-22
影响因子：
11.1
作者：
d'Avella, A;Bizzi, E
通讯作者：
Bizzi, E