Use of dehydrated human amniotic membrane allografts to promote healing in patients with refractory non healing wounds.
Use of dehydrated human amniotic membrane allografts to promote healing in patients with refractory non healing wounds.
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DOI：
10.1111/iwj.12035
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发表时间：
2014-12
影响因子：
3.1
通讯作者：
Fetterolf DE
中科院分区：
文献类型：
--
作者：
Sheikh ES;Sheikh ES;Fetterolf DE
不愈合的伤口带来了重大的社会和经济负担。据估计，慢性不愈合伤口在其一生中影响多达1-2%的个体，并且在国家和全球基础上每年占数十亿美元的费用。我们的目的是描述一种新的脱水羊膜同种异体移植物（EpiFix ®; MiMedx Group，Inc.，肯尼索，GA）用于治疗慢性不愈合伤口。我们描述了四名患者的EpiFix治疗结果，这些患者在保守和先进措施下均未实现伤口闭合，并已被转诊接受明确的整形外科手术。应用脱水羊膜材料一到三次，在各种伤口中观察到愈合。患者对该材料的耐受性良好。在长期随访中，愈合的伤口未复发。应考虑进一步研究脱水羊膜在各种类型皮肤伤口中的广泛应用。
Non healing wounds present a significant social and economic burden. Chronic non healing wounds are estimated to affect as many as 1–2% of individuals during their lifetime, and account for billions of dollars of expense annually on both a national and global basis. Our purpose is to describe the use of a novel dehydrated amniotic membrane allograft (EpiFix ®; MiMedx Group, Inc., Kennesaw, GA) for the treatment of chronic non healing wounds. We describe the results of EpiFix treatment in four patients who had not achieved wound closure with both conservative and advanced measures, and had been referred for a definitive plastic surgery procedure. Healing was observed in a variety of wounds with one to three applications of the dehydrated amniotic membrane material. The material was well tolerated by patients. Healed wounds did not recur in long‐term follow‐up. Further investigation of the use of dehydrated amniotic membrane in broader application to various types of dermal wounds should be considered.
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影响因子：
158.5
作者：
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通讯作者：
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