An interactive sports video game as an intervention for rehabilitation of community-living patients with schizophrenia: A controlled, single-blind, crossover study.
An interactive sports video game as an intervention for rehabilitation of community-living patients with schizophrenia: A controlled, single-blind, crossover study.
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DOI：
10.1371/journal.pone.0187480
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发表时间：
2017
期刊：
影响因子：
3.7
通讯作者：
Hirai T
中科院分区：
文献类型：
--
作者：
Shimizu N;Umemura T;Matsunaga M;Hirai T
额下是执行功能表现时前额叶皮层脑血流量减少的一种状态；这常见于精神分裂症患者。认知功能障碍以及精神分裂症的心理症状会影响患者重新融入社会的能力。目前的研究调查了互动体育视频游戏（IVG；任天堂Wii™运动度假村）对精神分裂症患者额叶功能的影响。8例患者（男6例，女2例，平均年龄46.7岁，标准差(SD) = 13.7）在对照、单盲、交叉研究中每周进行IVG，为期3个月。在干预前后，我们使用功能近红外光谱（fNIRS）检查额叶血流量，并使用额叶评估电池、健康相关生活质量量表和行为评估身体功能测试评估功能变化。fNIRS显示，在IVG期间，与对照组相比，IVG期间前额叶活动显著增加。此外，在IVG过程中，观察到不同通道的脑血流变化具有显著相关性。此外，我们观察到IVG后与健康相关的生活质量的干预相关改善。IVG干预与精神分裂症患者前额皮质激活增加和健康相关生活质量改善有关。慢性精神分裂症患者的特点是退缩和缺乏社会反应或对他人的兴趣。使用IVG的干预可能为这类患者提供一种有用的低成本康复方法，而不需要专门的设备。
Hypofrontality is a state of decreased cerebral blood flow in the prefrontal cortex during executive function performance; it is commonly observed in patients with schizophrenia. Cognitive dysfunction, as well as the psychological symptoms of schizophrenia, influences the ability of patients to reintegrate into society. The current study investigated the effects of an interactive sports video game (IVG; Nintendo Wii™ Sports Resort) on frontal lobe function of patients with schizophrenia. A sample of eight patients (6 male and 2 female; mean age = 46.7 years, standard deviation (SD) = 13.7) engaged in an IVG every week for 3 months in a controlled, single-blind, crossover study. Before and after the intervention we examined frontal lobe blood-flow volume using functional near-infrared spectroscopy (fNIRS), and assessed functional changes using the Frontal Assessment Battery, Health-Related Quality of Life scale, and behaviorally-assessed physical function tests. fNIRS revealed that prefrontal activity during IVG performance significantly increased in the IVG period compared with the control period. Furthermore, significant correlations between cerebral blood flow changes in different channels were observed during IVG performance. In addition, we observed intervention-related improvement in health-related quality of life following IVG. IVG intervention was associated with increased prefrontal cortex activation and improved health-related quality of life performance in patients with schizophrenia. Patients with chronic schizophrenia are characterized by withdrawal and a lack of social responsiveness or interest in others. Interventions using IVG may provide a useful low-cost rehabilitation method for such patients, without the need for specialized equipment.
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影响因子：
7.2
作者：
Fukuhara, S;Bito, S;Kurokawa, K
通讯作者：
Kurokawa, K
影响因子：
--
作者：
Minzenberg, Michael J.;Laird, Angela R.;Thelen, Sarah;Carter, Cameron S.;Glahn, David C.
通讯作者：
Glahn, David C.
DOI：
10.1111/j.1532-5415.1992.tb02068.x
发表时间：
1992-03-01
影响因子：
6.3
作者：
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通讯作者：
STUDENSKI, SA
影响因子：
9.9
作者：
YOSHITAKE, T;KIYOHARA, Y;FUJISHIMA, M
通讯作者：
FUJISHIMA, M
影响因子：
3.2
作者：
BRIGGS, RC;GOSSMAN, MR;SHADDEAU, SA
通讯作者：
SHADDEAU, SA