One-Pot Synthesis of 3,4-Dihydro-2(H)-Pyrimidinones Catalyzed by Reusable Acidic Choline-Based Ionic Liquids
One-Pot Synthesis of 3,4-Dihydro-2(H)-Pyrimidinones Catalyzed by Reusable Acidic Choline-Based Ionic Liquids
复制标题
可重复使用的酸性胆碱基离子液体催化一锅法合成3,4-二氢-2(H)-嘧啶酮
DOI：
10.1007/s10562-013-0978-6
复制
发表时间：
2013-02
影响因子：
2.8
通讯作者：
Wang, Jianji
中科院分区：
文献类型：
--
作者：
Zhu, Anlian;Li, Qianqian;Li, Lingjun;Wang, Jianji
本文合成了一系列胆碱基离子液体。结果表明，阳离子和阴离子对催化剂的热稳定性、酸性等性质以及催化剂合成3，4-二氢-2（H）-嘧啶酮的性能均有显著影响。[DMEA][HSO_4]离子液体催化体系具有底物耐受性广、反应条件温和、后处理方便、可重复使用等优点，其催化Biginelli反应的热稳定性、酸度和催化活性均按[DMEA][HSO_4][DMEA][H_2 PO_4][胆碱][H_2 PO_4]的顺序排列。
A series of choline-based ionic liquids (CIL) have been synthesized in this work. The results suggested that both the cations and the anions have significant influences on their properties such as thermostabilities, acidities and their performances for the synthesis of 3,4-dihydro-2(H)-pyrimidinones. The optimized catalytic system based on the CIL [DMEA][HSO4] for the Biginelli reactions benefits from the wide substrates tolerance, benign reaction conditions, easy work-up procedures, and the feasible reusability of the ionic liquid.Graphical AbstractThe thermostabilities, acidities, and the catalytic activities for the Biginelli reactions are all follows the sequence of [DMEA][HSO4] > [Choline] [HSO4] > [DMEA][H2PO4] > [Choline] [H2PO4].
登录
查看更多内容
锌基离子液体介导的醇直接亲核取代反应
影响因子：
9.8
作者：
Zhu, Anlian;Li, Lingjun;Wang, Jianji;Zhuo, Kelei
通讯作者：
Zhuo, Kelei
影响因子：
2.1
作者：
A. Hajipour;M. Seddighi
通讯作者：
A. Hajipour;M. Seddighi
影响因子：
64.8
作者：
Cooper, ER;Andrews, CD;Morris, RE
通讯作者：
Morris, RE
影响因子：
15
作者：
D. King;R. Mantz;R. Osteryoung
通讯作者：
D. King;R. Mantz;R. Osteryoung
影响因子：
15
作者：
Abbott, AP;Boothby, D;Rasheed, RK
通讯作者：
Rasheed, RK