Nematicidal activity of Paecilomyces spp. and isolation of a novel active compound
Nematicidal activity of Paecilomyces spp. and isolation of a novel active compound
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拟青霉属的杀线虫活性。
DOI：
10.1007/s12275-009-0012-2
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发表时间：
2009-06
影响因子：
3
通讯作者：
Liu, Ya-Jun
中科院分区：
文献类型：
--
作者：
Zhai, Chong-Yan;Liu, Yi;Zhang, Ke-Qin;Liu, Ya-Jun
拟青霉属的许多种是虫生真菌，并且有几种对线虫有效。为了研究拟青霉属真菌对线虫的控制潜力，对40种拟青霉属真菌的真菌提取物进行了分离纯化。评价了它们对松材线虫（Bursaphelenchus xylophilus）和Panagrellus redivus的杀线虫活性。对6种拟青霉的提取物进行了比较。11种植物对B具有杀线虫活性。木生植物菌株1.01761的甲醇提取物在Czapek固体培养基上培养24 h后，对灰潜蝇的杀灭率为95%以上;菌株1.01788的滤液在沙氏肉汤培养基上培养24 h后，对B的杀灭率为90%以上。在5 mg/ml浓度下，24 h后，从拟青霉（Paecilomyces sp.）YMF 1.01761中分离得到一个新的杀线虫化合物4-（4′-羧基-2 ′-乙基-羟基戊基）-5，6-二氢-6-甲基环丁[B]吡啶-3，6-二甲酸。24 h内，该化合物对马铃薯红腐病菌、南方根结线虫和B的LD_（50）分别为50.86 mg/L、47.1 mg/L和47.1 mg/L。松材线虫为167.7mg/L。
Many species of Paecilomyces are entomogenous fungi and several are efficacious toward nematodes. To study the potential of Paecilomyces species in controlling nematodes, fungal extracts of 40 Paecilomyces spp. were evaluated for their nematicidal activity against Bursaphelenchus xylophilus and Panagrellus redivivus. The extracts of six Paecilomyces spp. exhibited the nematicidal activity against P. redivivus, and 11 species exhibited the nematicidal activity against B. xylophilus. The methanol extract of strain 1.01761 incubating on Czapek solid medium killed more than 95% P. redivivus in 24 h at 5 mg/ml, and the filtrate of strain 1.01788 cultured in Sabouraud’s broth medium resulted in 90% mortality of B. xylophilus in 24 h at 5 mg/ml. A novel nematicidal compound 4-(4′-carboxy-2′-ethyl-hydroxypentyl)-5,6-dihydro-6-methylcyclobuta[b]pyridine-3,6-dicarboxylic acid, was isolated from Paecilomyces sp. YMF1.01761. The LD50 value of the compound within 24 h against P. redivivus was 50.86 mg/L, against Meloidogyne incognita was 47.1 mg/L, and against B. xylophilus was 167.7 mg/L.
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DOI：
--
发表时间：
2002
期刊：
--
影响因子：
--
作者：
B. Kerry;J. Bourne
通讯作者：
B. Kerry;J. Bourne
影响因子：
9.7
作者：
GRAY, NF
通讯作者：
GRAY, NF
DOI：
10.1139/b87-103
发表时间：
1987-04-01
期刊：
CANADIAN JOURNAL OF BOTANY-REVUE CANADIENNE DE BOTANIQUE
影响因子：
--
作者：
BARRON, GL;THORN, RG
通讯作者：
THORN, RG
影响因子：
1.3
作者：
P. Jatala;R. Kaltenbach;M. Bocángel
通讯作者：
P. Jatala;R. Kaltenbach;M. Bocángel
影响因子：
5
作者：
Asaff, A;Cerda-García-Rojas, C;de la Torre, M
通讯作者：
de la Torre, M