The evaluation of NIR-absorbing porphyrin derivatives as contrast agents in photoacoustic imaging.
The evaluation of NIR-absorbing porphyrin derivatives as contrast agents in photoacoustic imaging.
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DOI：
10.1039/c3cp52193a
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发表时间：
2013-11-14
期刊：
影响因子：
--
通讯作者：
Zhu Q
中科院分区：
文献类型：
--
作者：
Abuteen A;Zanganeh S;Akhigbe J;Samankumara LP;Aguirre A;Biswal N;Braune M;Vollertsen A;Röder B;Brückner C;Zhu Q
测试了六种游离碱四吡咯发色团、三种喹啉环化卟啉和三种吗啉菌绿素作为新型分子光声成像造影剂在组织模型中的功效，与基准造影剂ICG相比，可提供高达约2.5倍的造影增强。测试方案比较吸收大致相同的光能时的光声信号输出强度。染料的光物理参数和由此产生的光声信号强度之间的一些关系可以导出。
Six free base tetrapyrrolic chromophores, three quinoline-annulated porphyrins and three morpholinobacteriochlorins, that absorb light in the near-IR range and possess, in comparison to regular porphyrins, unusually low fluorescence emission and 1O2 quantum yields were tested with respect to their efficacy as novel molecular photo-acoustic imaging contrast agents in a tissue phantom, providing an up to ~2.5-fold contrast enhancement over that of the benchmark contrast agent ICG. The testing protocol compares the photoacoustic signal output strength upon absorption of approximately the same light energy. Some relationships between photophysical parameters of the dyes and the resulting photoacoustic signal strength could be derived.
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影响因子：
7.3
作者：
Huang, Ying-Ying;Mroz, Pawel;Zhiyentayev, Timur;Sharma, Sulbha K.;Balasubramanian, Thiagarajan;Ruzie, Christian;Krayer, Michael;Fan, Dazhong;Borbas, K. Eszter;Yang, Eunkyung;Kee, Hooi Ling;Kirmaier, Christine;Diers, James R.;Bocian, David F.;Holten, Dewey;Lindsey, Jonathan S.;Hamblin, Michael R.
通讯作者：
Hamblin, Michael R.
用于活体小鼠高灵敏度和多重研究的增强型光声成像剂系列。
影响因子：
17.1
作者：
de la Zerda A;Bodapati S;Teed R;May SY;Tabakman SM;Liu Z;Khuri-Yakub BT;Chen X;Dai H;Gambhir SS
通讯作者：
Gambhir SS
影响因子：
19
作者：
Chen J;Yang M;Zhang Q;Cho EC;Cobley CM;Kim C;Glaus C;Wang LV;Welch MJ;Xia Y
通讯作者：
Xia Y
影响因子：
3.6
作者：
Hoelen, CGA;de Mul, FFM;Dekker, A
通讯作者：
Dekker, A
影响因子：
4.9
作者：
Huang, Liyi;Huang, Ying-Ying;Hamblin, Michael R.
通讯作者：
Hamblin, Michael R.