Gestational age at previous preterm birth does not affect cerclage efficacy.
Gestational age at previous preterm birth does not affect cerclage efficacy.
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DOI：
10.1016/j.ajog.2010.05.018
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发表时间：
2010-10
影响因子：
9.8
通讯作者：
Vaginal Ultrasound Trial Consortium
中科院分区：
文献类型：
--
作者：
Wing DA;Szychowski J;Owen J;Hankins G;Iams JD;Sheffield JS;Perez-Delboy A;Berghella V;Guzman ER;Vaginal Ultrasound Trial Consortium
目的：评估最早自然早产(SPTB)胎龄(GA)对宫颈长度(CL)、妊娠持续时间和后续妊娠超声提示的环扎效果的影响。NICHD的计划二次分析-CL<；25 mm环扎试验。17-33 6/7周至少有一次SPTB的妇女在16-23 6/7周期间接受了连续的阴道超声筛查；CL在合格的随机评估中被使用。我们观察到先前的SPTB GA和合格的CL之间存在显著的相关性(p=0.0008)。在线性回归模型中，当控制CL和环扎时，既不是先前的SPTB遗传，也不是环扎和先前出生的遗传的交互作用对以后出生的遗传有显著的预测作用。虽然在妊娠中期有25 mm大小的妇女中，先前的SPTB GA和CL之间存在关联，但在有较早SPTB史的妇女中，环扎似乎没有不成比例的好处。
To evaluate effect of earliest prior spontaneous preterm birth (SPTB) gestational age (GA) on cervical length (CL), pregnancy duration, and ultrasound-indicated cerclage efficacy in a subsequent gestation. Planned secondary analysis of the NICHD- trial of cerclage for CL < 25 mm. Women with at least one prior SPTB between 17-33 6/7 weeks underwent serial vaginal ultrasound screening between 16 and 23 6/7 weeks; CL at qualifying randomization evaluation was utilized. We observed a significant correlation (p=0.0008) between prior SPTB GA and qualifying CL. In a linear regression model when controlling for CL and cerclage, neither prior SPTB GA nor the interaction between cerclage and prior birth GA was significant predictor of subsequent birth GA. While there is an association between prior SPTB GA and CL in women with mid-trimester CL < 25 mm, there does not appear to be a disproportionate benefit of cerclage in women with earlier prior SPTB.
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影响因子：
7.1
作者：
Szychowski, J. M.;Owen, J.;Hankins, G.;Iams, J.;Sheffield, J.;Perez-Delboy, A.;Berghella, V.;Wing, D. A.;Guzman, E. R.
通讯作者：
Guzman, E. R.
影响因子：
9.8
作者：
Althuisius, SM;Dekker, GA;van Geijn, HP
通讯作者：
van Geijn, HP
影响因子：
9.8
作者：
Kiefer, Daniel G.;Keeler, Sean M.;Hanna, Nazeeh
通讯作者：
Hanna, Nazeeh
影响因子：
168.9
作者：
To, MS;Alfirevic, Z;Nicolaides, KH
通讯作者：
Nicolaides, KH
影响因子：
158.5
作者：
Cnattingius, S;Granath, F;Harlow, BL
通讯作者：
Harlow, BL