Maximising value from a United Kingdom Biomedical Research Centre: study protocol.
Maximising value from a United Kingdom Biomedical Research Centre: study protocol.
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DOI：
10.1186/s12961-017-0237-1
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发表时间：
2017-08-14
影响因子：
4
通讯作者：
Partnerships for Health, Wealth and Innovation cross-cutting theme of the National Institute for Health Research Biomedical Research Centre, Oxford
中科院分区：
文献类型：
--
作者：
Greenhalgh T;Ovseiko PV;Fahy N;Shaw S;Kerr P;Rushforth AD;Channon KM;Kiparoglou V;Partnerships for Health, Wealth and Innovation cross-cutting theme of the National Institute for Health Research Biomedical Research Centre, Oxford
生物医学研究中心（BRC）是英国医疗机构和大学之间的合作伙伴关系。他们的使命是创造新的治疗方法、技术、诊断和其他干预措施，以提高该国的国际竞争力，将这些创新迅速转化为患者的利益，并提高效率，减少医疗保健的浪费。随着NIHR牛津BRC（牛津BRC）进入第三个5年资助期，我们寻求（1）应用证据基础，研究如何最好地支持这个大型多利益相关者研究系统中的各种伙伴关系，以及（2）研究这些伙伴关系如何在新的，雄心勃勃的转化研究计划中发挥作用。组织案例研究，由行动研究的原则通知。一个跨领域的主题，“健康，财富和创新的伙伴关系”已经建立了多个子主题（药物开发，设备开发，业务支持和商业化，研究方法和统计，卫生经济学，生物伦理学，病人和公众参与和参与，知识转化，以及教育和培训），以支持BRC的个别研究主题，并产生跨主题的学习。“伙伴关系”主题将通过一系列参与平台和活动促进六种类型的伙伴关系（与患者和公民，临床服务，行业，整个NIHR基础设施，跨学科，以及政策制定者和支付者）来支持BRC的目标。我们将围绕典型案例研究开发纵向进展叙事，并应用创新研究（三重障碍），科学社会学（模式2知识生产）和商业研究（价值共创）的理论模型。数据来源将是BRC研究主题内的实证研究（将单独申请NHS伦理批准），加上文献分析和访谈以及研究利益相关者的人种学。本研究已通过牛津大学中央大学研究伦理委员会的伦理审查。我们预计这项工作将为牛津BRC增加重要价值。我们预测加速知识转化;创新过程与患者优先事项以及负责任的道德研究原则更加一致;减少研究浪费;有关多利益相关者研究伙伴关系及其运作环境的治理和活动的新知识;以及反映快速发展的卫生研究系统未来需求的能力建设。
Biomedical Research Centres (BRCs) are partnerships between healthcare organisations and universities in England. Their mission is to generate novel treatments, technologies, diagnostics and other interventions that increase the country’s international competitiveness, to rapidly translate these innovations into benefits for patients, and to improve efficiency and reduce waste in healthcare. As NIHR Oxford BRC (Oxford BRC) enters its third 5-year funding period, we seek to (1) apply the evidence base on how best to support the various partnerships in this large, multi-stakeholder research system and (2) research how these partnerships play out in a new, ambitious programme of translational research. Organisational case study, informed by the principles of action research. A cross-cutting theme, ‘Partnerships for Health, Wealth and Innovation’ has been established with multiple sub-themes (drug development, device development, business support and commercialisation, research methodology and statistics, health economics, bioethics, patient and public involvement and engagement, knowledge translation, and education and training) to support individual BRC research themes and generate cross-theme learning. The ‘Partnerships’ theme will support the BRC’s goals by facilitating six types of partnership (with patients and citizens, clinical services, industry, across the NIHR infrastructure, across academic disciplines, and with policymakers and payers) through a range of engagement platforms and activities. We will develop a longitudinal progress narrative centred around exemplar case studies, and apply theoretical models from innovation studies (Triple Helix), sociology of science (Mode 2 knowledge production) and business studies (Value Co-creation). Data sources will be the empirical research studies within individual BRC research themes (who will apply separately for NHS ethics approval), plus documentary analysis and interviews and ethnography with research stakeholders. This study has received ethics clearance through the University of Oxford Central University Research Ethics Committee. We anticipate that this work will add significant value to Oxford BRC. We predict accelerated knowledge translation; closer alignment of the innovation process with patient priorities and the principles of responsible, ethical research; reduction in research waste; new knowledge about the governance and activities of multi-stakeholder research partnerships and the contexts in which they operate; and capacity-building that reflects the future needs of a rapidly-evolving health research system.
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影响因子：
7.2
作者：
Etzkowitz, H;Leydesdorff, L
通讯作者：
Leydesdorff, L
影响因子：
3
作者：
Bresnen, Mike;Burrell, Gibson
通讯作者：
Burrell, Gibson
影响因子：
2.4
作者：
Edelman N;Barron D
通讯作者：
Barron D
影响因子：
5.4
作者：
Fitzgerald, Louise;Harvey, Gill
通讯作者：
Harvey, Gill
影响因子：
2
作者：
Flyvbjerg, B
通讯作者：
Flyvbjerg, B