Spasms after spinal cord injury show low-frequency intermuscular coherence.
Spasms after spinal cord injury show low-frequency intermuscular coherence.
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DOI：
10.1152/jn.00112.2018
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发表时间：
2018-10-01
影响因子：
2.5
通讯作者：
Thomas CK
中科院分区：
文献类型：
--
作者：
Aguiar SA;Baker SN;Gant K;Bohorquez J;Thomas CK
肌肉间的连贯性允许研究肌肉群的共同输入。尽管β频段(15-30赫兹)的肌肉间连贯性被认为起源于大脑皮层，但在较低频率下的肌间连贯性的来源仍不清楚。我们使用了一种可穿戴设备，记录了7名脊髓损伤患者(美国脊髓损伤协会损害分级：A，6名；B，1名)的四条腿肌在24小时内的肌电(EMG)信号，同时进行了正常的日常生活活动。我们检测了在这些持续时间较长的记录中发生的自然痉挛，并计算了所有六种可能的肌肉对组合之间的肌肉间一致性。在2至13赫兹的低频下，肌肉间有显著的连贯性。最有可能的来源是脊髓及其外围反馈环，因为这些患者的脊柱病变中断了与脊柱上结构的连接。这是第一个证明脊髓能够产生低频肌肉间连贯性并严重减少或取消下行驱动的报告。新的和值得注意的是，这是第一个报告，证明肌肉之间的连贯性，在低频率下，可以产生肌肉之间的脊髓严重减少或取消下行驱动。
Intermuscular coherence allows the investigation of common input to muscle groups. Although beta-band (15–30 Hz) intermuscular coherence is well understood as originating from the cortex, the source of intermuscular coherence at lower frequencies is still unclear. We used a wearable device that recorded electromyographic (EMG) signals during a 24-h period in four lower limb muscles of seven spinal cord injury patients (American Spinal Cord Injury Association impairment scale: A, 6 subjects; B, 1 subject) while they went about their normal daily life activities. We detected natural spasms occurring during these long-lasting recordings and calculated intermuscular coherence between all six possible combinations of muscle pairs. There was significant intermuscular coherence at low frequencies, between 2 and 13 Hz. The most likely source for this was the spinal cord and its peripheral feedback loops, because the spinal lesions in these patients had interrupted connections to supraspinal structures. This is the first report to demonstrate that the spinal cord is capable of producing low-frequency intermuscular coherence with severely reduced or abolished descending drive. NEW & NOTEWORTHY This is the first report to demonstrate that intermuscular coherence between lower limb muscles at low frequencies can be produced by the spinal cord with severely reduced or abolished descending drive.
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DOI：
10.1093/brain/aws150
发表时间：
2012-09
期刊：
Brain : a journal of neurology
影响因子：
--
作者：
Fisher KM;Zaaimi B;Williams TL;Baker SN;Baker MR
通讯作者：
Baker MR
影响因子：
2.9
作者：
Boonstra TW
通讯作者：
Boonstra TW
人类运动皮质输出的塑性变化是由随机但不是闭环外围刺激引起的：因果关系的诅咒。
影响因子：
2.9
作者：
Brown KI;Williams ER;de Carvalho F;Baker SN
通讯作者：
Baker SN
影响因子：
3.4
作者：
Cremoux, Sylvain;Tallet, Jessica;Amarantini, David
通讯作者：
Amarantini, David
影响因子：
3.4
作者：
Bannatyne, BA;Edgley, SA;Maxwell, DJ
通讯作者：
Maxwell, DJ