Postural orthostatic tachycardia syndrome (POTS) and other autonomic disorders after COVID-19 infection: a case series of 20 patients.
Postural orthostatic tachycardia syndrome (POTS) and other autonomic disorders after COVID-19 infection: a case series of 20 patients.
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DOI：
10.1007/s12026-021-09185-5
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发表时间：
2021-04
影响因子：
4.4
通讯作者：
Whitelaw S
中科院分区：
文献类型：
--
作者：
Blitshteyn S;Whitelaw S
描述SARS-CoV-2感染（COVID-19）后新发体位性站立性心动过速综合征（POTS）和其他自主神经疾病患者的临床特征、诊断结果、治疗和结局。我们回顾性回顾了2020年4月至12月感染COVID-19后出现持续神经系统和心血管疾病的患者的医疗记录。本研究纳入20例患者（70%为女性）。15例有POTS， 3例有神经心源性晕厥，2例有直立性低血压。6例患者心脏或肺部检查异常，4例自身免疫或炎症标志物升高。所有患者均接受非药物治疗，大多数患者需要药物治疗。在COVID-19后6至8个月，17例（85%）患者有残留的自主神经症状，12例（60%）患者无法重返工作岗位。POTS可以在先前健康的患者中跟随COVID-19。适当的诊断调查和治疗对于识别和治疗COVID-19后的自主神经功能障碍是必要的。
To describe clinical features, diagnostic findings, treatments, and outcomes in patients with new-onset postural orthostatic tachycardia syndrome (POTS) and other autonomic disorders following SARS-CoV-2 infection (COVID-19). We retrospectively reviewed medical records for patients who presented with persistent neurologic and cardiovascular complaints between April and December 2020 following COVID-19 infection. Twenty patients (70% female) were included in this study.Fifteen had POTS, 3 had neurocardiogenic syncope, and 2 had orthostatic hypotension. Six patients had abnormalities on cardiac or pulmonary testing, and 4 had elevated autoimmune or inflammatory markers. All patients were treated with non-pharmacologic therapies, and most required pharmacologic therapies. Six to 8 months after COVID-19, 17 (85%) patients had residual autonomic symptoms, with 12 (60%) unable to return to work. POTS can follow COVID-19 in previously healthy patients. Appropriate diagnostic investigations and therapies are necessary to identify and treat autonomic dysfunction after COVID-19.
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影响因子：
2.6
作者：
Blitshteyn, S.
通讯作者：
Blitshteyn, S.
影响因子：
5.3
作者：
Watari M;Nakane S;Mukaino A;Nakajima M;Mori Y;Maeda Y;Masuda T;Takamatsu K;Kouzaki Y;Higuchi O;Matsuo H;Ando Y
通讯作者：
Ando Y
影响因子：
--
作者：
Novak P
通讯作者：
Novak P
影响因子：
5.4
作者：
Gunning, William T., III;Kvale, Heather;Grubb, Blair P.
通讯作者：
Grubb, Blair P.
DOI：
10.19102/icrm.2020.111102
发表时间：
2020-11
期刊：
The Journal of innovations in cardiac rhythm management
影响因子：
--
作者：
Kanjwal K;Jamal S;Kichloo A;Grubb BP
通讯作者：
Grubb BP