PHO85, a negative regulator of the PHO system, is a homolog of the protein kinase gene, CDC28, of Saccharomyces cerevisiae
PHO85, a negative regulator of the PHO system, is a homolog of the protein kinase gene, CDC28, of Saccharomyces cerevisiae
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PHO85 是 PHO 系统的负调节因子，是酿酒酵母蛋白激酶基因 CDC28 的同源物
DOI：
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发表时间：
1988
期刊：
影响因子：
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通讯作者：
R. Wickner
中科院分区：
文献类型：
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作者：
A. Toh;Kazuma Tanaka;Yukifumi Uesono;R. Wickner
PHO85基因编码酿酒酵母pho系统的负性调节因子之一，其产物与CDC28蛋白激酶具有显著的氨基酸序列同源性。然而，过表达PHO85并不能抑制cdc28-1突变的温度敏感表型。PHO85基因的核苷酸序列强烈表明在编码N-末端区域的序列附近存在内含子。
SummaryThe product of the PHO85 gene, which encodes one of the negative regulatory factors of the PHO system in Saccharomyces cerevisiae, shows significant amino acid sequence homology with the CDC28 protein kinase. However, overexpressing PHO85 did not suppress the temperature sensitive phenotype of the cdc28-1 mutation. The nucleotide sequence of the PHO85 gene strongly suggests the presence of an intron near the sequence encoding the N-terminal region.
影响因子：
56.9
作者：
CELENZA, JL;CARLSON, M
通讯作者：
CARLSON, M