Evaluating the Efficacy of Automated Smoking Treatment for People With HIV: Protocol for a Randomized Controlled Trial.
Evaluating the Efficacy of Automated Smoking Treatment for People With HIV: Protocol for a Randomized Controlled Trial.
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DOI：
10.2196/33183
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发表时间：
2021-11-17
影响因子：
1.7
通讯作者：
Vidrine JI
中科院分区：
文献类型：
--
作者：
Vidrine DJ;Bui TC;Businelle MS;Shih YT;Sutton SK;Shahani L;Hoover DS;Bowles K;Vidrine JI
艾滋病毒感染者的吸烟率几乎是普通人群的3倍。然而，文献中很少报道针对携带艾滋病毒的吸烟者的戒烟试验。需要努力为艾滋病毒感染者制定和评估可持续、低成本和基于证据的戒烟干预措施。鉴于移动电话的广泛普及，使用移动健康应用程序提高戒烟干预措施的覆盖面和有效性的潜力是有希望的，但缺乏有效性的证据，特别是在艾滋病毒感染者中。本研究将包括一项两组随机对照试验，以评估对寻求戒烟治疗的艾滋病毒感染者进行全自动智能手机干预的效果。参与者（N=500）将随机接受标准治疗（ST; 250/500, 50%）或自动治疗（AT; 250/500, 50%）。ST参与者将连接到佛罗里达戒烟热线，并将接受透皮贴片和含片形式的尼古丁替代疗法。这种方法被称为“询问、建议、连接”，由我们的团队开发，并已在许多卫生系统中实施。ST将与全自动行为治疗方法AT进行比较。AT参与者将接受尼古丁替代疗法和基于智能手机的交互式干预，包括量身定制的视听和文本内容。主要目标是确定AT在促进长期戒烟方面是否比资源更密集的ST方法表现更好。我们的主要目的是评估AT在促进艾滋病毒感染者戒烟方面的功效。作为次要目标，我们将探索潜在的中介和调节因素，并进行经济评估，以评估与st相比，AT的成本和成本效益。招生和注册将于2021年秋季开始。迫切需要为吸烟的艾滋病毒感染者提供有效、具有成本效益和可持续的戒烟治疗。AT干预旨在帮助满足这一需求。如果确定有效性，辅助疗法方法将很容易被艾滋病毒诊所和社区组织采用，它将提供一种有效的方式，将有限的公共卫生资源分配给烟草控制干预措施。ClinicalTrials.gov NCT05014282;https://clinicaltrials.gov/ct2/show/NCT05014282 prr1 - 10.2196/33183
Smoking prevalence rates among people with HIV are nearly 3 times higher than those in the general population. Nevertheless, few smoking cessation trials targeting smokers with HIV have been reported in the literature. Efforts to develop and evaluate sustainable, low-cost, and evidence-based cessation interventions for people with HIV are needed. Given the widespread proliferation of mobile phones, the potential of using mobile health apps to improve the reach and efficacy of cessation interventions is promising, but evidence of efficacy is lacking, particularly among people with HIV. This study will consist of a 2-group randomized controlled trial to evaluate a fully automated smartphone intervention for people with HIV seeking cessation treatment. Participants (N=500) will be randomized to receive either standard treatment (ST; 250/500, 50%) or automated treatment (AT; 250/500, 50%). ST participants will be connected to the Florida Quitline and will receive nicotine replacement therapy in the form of transdermal patches and lozenges. This approach, referred to as Ask Advise Connect, was developed by our team and has been implemented in numerous health systems. ST will be compared with AT, a fully automated behavioral treatment approach. AT participants will receive nicotine replacement therapy and an interactive smartphone-based intervention that comprises individually tailored audiovisual and text content. The major goal is to determine whether AT performs better in terms of facilitating long-term smoking abstinence than the more resource-intensive ST approach. Our primary aim is to evaluate the efficacy of AT in facilitating smoking cessation among people with HIV. As a secondary aim, we will explore potential mediators and moderators and conduct economic evaluations to assess the cost and cost-effectiveness of AT compared with ST. The intervention content has been developed and finalized. Recruitment and enrollment will begin in the fall of 2021. There is a critical need for efficacious, cost-effective, and sustainable cessation treatments for people with HIV who smoke. The AT intervention was designed to help fill this need. If efficacy is established, the AT approach will be readily adoptable by HIV clinics and community-based organizations, and it will offer an efficient way to allocate limited public health resources to tobacco control interventions. ClinicalTrials.gov NCT05014282; https://clinicaltrials.gov/ct2/show/NCT05014282 PRR1-10.2196/33183
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影响因子：
5
作者：
COHEN, S;KAMARCK, T;MERMELSTEIN, R
通讯作者：
MERMELSTEIN, R
DOI：
10.1016/0749-5978(91)90020-t
发表时间：
1991-12-01
影响因子：
4.6
作者：
AJZEN, I
通讯作者：
AJZEN, I
影响因子：
3.5
作者：
Aigner CJ;Gritz ER;Tamí-Maury I;Baum GP;Arduino RC;Vidrine DJ
通讯作者：
Vidrine DJ
影响因子：
5.9
作者：
CURRY, SJ;WAGNER, EH;GROTHAUS, LC
通讯作者：
GROTHAUS, LC
DOI：
10.1186/s12962-021-00262-y
发表时间：
2021-02-15
期刊：
Cost effectiveness and resource allocation : C/E
影响因子：
--
作者：
Cobos-Campos R;Mar J;Apiñaniz A;de Lafuente AS;Parraza N;Aizpuru F;Orive G
通讯作者：
Orive G