Natural history of tuberculosis: duration and fatality of untreated pulmonary tuberculosis in HIV negative patients: a systematic review.
Natural history of tuberculosis: duration and fatality of untreated pulmonary tuberculosis in HIV negative patients: a systematic review.
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结核病的自然病史:艾滋病毒阴性患者未经治疗的肺结核的持续时间和死亡:系统评价。
DOI:
10.1371/journal.pone.0017601
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发表时间:
2011-04-04
期刊:
影响因子:
3.7
通讯作者:
Nagelkerke NJ
中科院分区:
文献类型:
--
作者:
Tiemersma EW;van der Werf MJ;Borgdorff MW;Williams BG;Nagelkerke NJ
The prognosis, specifically the case fatality and duration, of untreated tuberculosis is important as many patients are not correctly diagnosed and therefore receive inadequate or no treatment. Furthermore, duration and case fatality of tuberculosis are key parameters in interpreting epidemiological data. To estimate the duration and case fatality of untreated pulmonary tuberculosis in HIV negative patients we reviewed studies from the pre-chemotherapy era. Untreated smear-positive tuberculosis among HIV negative individuals has a 10-year case fatality variously reported between 53% and 86%, with a weighted mean of 70%. Ten-year case fatality of culture-positive smear-negative tuberculosis was nowhere reported directly but can be indirectly estimated to be approximately 20%. The duration of tuberculosis from onset to cure or death is approximately 3 years and appears to be similar for smear-positive and smear-negative tuberculosis. Current models of untreated tuberculosis that assume a total duration of 2 years until self-cure or death underestimate the duration of disease by about one year, but their case fatality estimates of 70% for smear-positive and 20% for culture-positive smear-negative tuberculosis appear to be satisfactory.
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DOI:
10.1007/bf02152328
发表时间:
1951-01-01
期刊:
Beitrage zur Klinik der Tuberkulose und spezifischen Tuberkulose-Forschung
影响因子:
--
作者:
BERG, G
通讯作者:
BERG, G
影响因子:
3.3
作者:
BREWSTER, AW;FLETCHER, RC;FLETCHER, AB
通讯作者:
FLETCHER, AB
影响因子:
3.3
作者:
COMSTOCK, GW;BURKE, MH
通讯作者:
BURKE, MH
影响因子:
11.8
作者:
Akksilp S;Karnkawinpong O;Wattanaamornkiat W;Viriyakitja D;Monkongdee P;Sitti W;Rienthong D;Siraprapasiri T;Wells CD;Tappero JW;Varma JK
通讯作者:
Varma JK
DOI:
10.1016/s0041-3879(34)80211-5
发表时间:
1935-01-01
期刊:
Tubercle
影响因子:
--
作者:
Cochrane, E.
通讯作者:
Cochrane, E.