Approaches to the study of neural coding of sound source location and sound envelope in real environments

Approaches to the study of neural coding of sound source location and sound envelope in real environments
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真实环境中声源位置和声音包络的神经编码研究方法

DOI:
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发表时间:
2012
期刊:
Front. Neural Circuits
影响因子:
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通讯作者:
Duck O. Kim
Duck O. Kim
中科院分区:
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文献类型:
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作者:
S. Kuwada;Brian B. Bishop;Duck O. Kim

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听觉系统的主要功能是识别(什么是声音)和定位(声音在哪里)。尽管其中每一个都受到了相当多的关注,但很少将它们结合起来进行研究。此外,大量研究中使用的刺激并不代表真实环境中的声音位置,并且忽略了混响的影响。另一个被忽视的维度是声源的距离。最后,缺乏对未麻醉动物进行的研究。我们阐述了一套克服这些缺点的有效方法。我们利用虚拟听觉空间方法(VAS)来高效呈现不同方位、不同距离、不同环境下的声音。此外,该方法允许在双耳和单耳刺激之间进行有效切换,并单独或组合改变声音提示,以阐明定位和识别背后的神经机制。此类程序无法通过真实的声场刺激来执行。我们的研究旨在解决以下问题:IC 神经元是否专门处理什么、在哪里的听觉信息?声源的混响和距离如何影响此处理? IC神经元如何表示声源距离?包络处理背后的神经机制是双耳还是单耳?
The major functions of the auditory system are recognition (what is the sound) and localization (where is the sound). Although each of these has received considerable attention, rarely are they studied in combination. Furthermore, the stimuli used in the bulk of studies did not represent sound location in real environments and ignored the effects of reverberation. Another ignored dimension is the distance of a sound source. Finally, there is a scarcity of studies conducted in unanesthetized animals. We illustrate a set of efficient methods that overcome these shortcomings. We use the virtual auditory space method (VAS) to efficiently present sounds at different azimuths, different distances and in different environments. Additionally, this method allows for efficient switching between binaural and monaural stimulation and alteration of acoustic cues singly or in combination to elucidate neural mechanisms underlying localization and recognition. Such procedures cannot be performed with real sound field stimulation. Our research is designed to address the following questions: Are IC neurons specialized to process what and where auditory information? How does reverberation and distance of the sound source affect this processing? How do IC neurons represent sound source distance? Are neural mechanisms underlying envelope processing binaural or monaural?
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