Phase-sensitive sodium B1 mapping.

Phase-sensitive sodium B1 mapping.
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DOI:
10.1002/mrm.22700
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发表时间:
2011-04
影响因子:
3.3
通讯作者:
Bangerter, Neal K.
Bangerter, Neal K.
中科院分区:
医学3区
文献类型:
--
作者:
Allen, Steven P.;Morrell, Glen R.;Peterson, Brock;Park, Danny;Gold, Garry E.;Kaggie, Joshua D.;Bangerter, Neal K.

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定量钠 MRI 需要准确了解影响钠信号的因素。钠信号电平的一个重要决定因素是发射 B1 场强。然而,钠 MRI 典型的低信噪比使得在合理的扫描时间内准确进行 B1 映射具有挑战性。最近,一种新的相敏 B1 映射技术被证明在低信噪比情况下和更广泛的翻转角范围内比广泛使用的双角度方法效果更好。在这项工作中,相敏 B1 映射技术应用于钠,并通过模拟和模型研究将其性能与双角度方法进行比较。与双角度方法相比,相敏方法可以在低信噪比下产生更高质量的 B1 图,并且测量的一致性更高。还显示了人体乳房的体内钠 B1 图,证明了相敏方法在人体研究中的可行性。
Quantitative sodium MRI requires accurate knowledge of factors affecting the sodium signal. One important determinant of sodium signal level is the transmit B1 field strength. However, the low signal-to-noise ratio typical of sodium MRI makes accurate B1 mapping in reasonable scan times challenging. A new phase-sensitive B1 mapping technique has recently been shown to work better than the widely used dual-angle method in low-signal-to-noise ratio situations and over a broader range of flip angles. In this work, the phase-sensitive B1 mapping technique is applied to sodium, and its performance compared to the dual-angle method through both simulation and phantom studies. The phase-sensitive method is shown to yield higher quality B1 maps at low signal-to-noise ratio and greater consistency of measurement than the dual-angle method. An in vivo sodium B1 map of the human breast is also shown, demonstrating the phase-sensitive method’s feasibility for human studies.
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