Disparities in vaccination rates in solid organ transplant patients.

Disparities in vaccination rates in solid organ transplant patients.
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DOI:
10.1111/tid.14010
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发表时间:
2023-04
影响因子:
2.6
通讯作者:
Kennedy, Cassie C.
Kennedy, Cassie C.
中科院分区:
医学4区
文献类型:
--
作者:
Felzer, Jamie R.;Finney Rutten, Lila J.;Wi, Chung-Il;LeMahieu, Allison M.;Beam, Elena;Juhn, Young J.;Jacobson, Robert M.;Kennedy, Cassie C.

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预防肺炎链球菌和流感等可预防呼吸道感染的疫苗接种对免疫抑制实体器官移植(SOT)受者很重要。对于年龄、种族、民族、性别和社会人口因素(包括农村性或社会经济地位)与该人群疫苗接种相关的作用知之甚少。我们使用罗切斯特流行病学项目(一个医疗记录链接系统)进行了一项基于人群的研究,以评估居住在明尼苏达州东南部四个县的成人实体器官移植接受者(19-64岁)中流感和肺炎球菌疫苗接种率相关的社会经济和人口统计学因素。2010年6月1日至2020年6月30日期间的疫苗接种数据来自明尼苏达州免疫信息连接。用泊松模型和logistic回归模型评估疫苗接种率。共有468名SOT接种者被确定,总体流感疫苗接种率为57%-63%,肺炎球菌疫苗接种率为56%。正如预期的那样,接种肺炎球菌疫苗与接种流感疫苗正相关。即使在调整了年龄、性别、种族、民族和社会经济地位之后,农村患者的疫苗接种率也比城市患者低。虽然人口主要是白人和非西班牙裔,但接种疫苗没有因种族或民族而不同,但流感疫苗接种却因SES而不同。在器官移植组中,接受肝脏和肺部移植的人接种流感疫苗的比例最低,接受心脏移植的人接种肺炎球菌疫苗的比例最低。疫苗接种率低于国家目标。农村与疫苗接种不足有关。需要进一步的调查来了解和解决移植受者接种疫苗的障碍。
Vaccinations against preventable respiratory infections such as Streptococcus pneumoniae and influenza are important in immunosuppressed solid organ transplant (SOT) recipients. Little is known about the role of age, race, ethnicity, sex, and sociodemographic factors including rurality, or socioeconomic status (SES) associated with vaccine uptake in this population. We conducted a population-based study using the Rochester Epidemiology Project, a medical records linkage system, to assess socioeconomic and demographic factors associated with influenza and pneumococcal vaccination rates among adult recipients of solid organ transplantation (aged 19–64 years) living in four counties in southeastern Minnesota. Vaccination data were obtained from the Minnesota Immunization Information Connection from June 1, 2010 to June 30, 2020. Vaccination rate was assessed with Poisson and logistic regression models. A total of 468 SOT recipients were identified with an overall vaccination rate of 57%–63% for influenza and 56% for pneumococcal vaccines. As expected, vaccination for pneumococcal vaccine positively correlated with influenza vaccination. Rural patients had decreased vaccination in both compared to urban patients, even after adjusting for age, sex, race, ethnicity, and SES. Although the population was mostly White and non-Hispanic, neither vaccination differed by race or ethnicity, but influenza vaccination did by SES. Among organ transplant groups, liver and lung recipients were least vaccinated for influenza, and heart recipients were least up-to-date on pneumococcal vaccines. Rates of vaccination were below national goals. Rurality was associated with undervaccination. Further investigation is needed to understand and address barriers to vaccination among transplant recipients.
DOI: 10.1111/ajt.16492
发表时间: 2021-02-01
影响因子: 8.8
作者:
Colvin, M.;Smith, J. M.;Kasiske, B. L.
通讯作者: Kasiske, B. L.
DOI: 10.1016/j.amjmed.2015.10.031
发表时间: 2016-06
期刊: The American journal of medicine
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作者:
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发表时间: 2021-02-01
影响因子: 8.8
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发表时间: 2022-02-01
影响因子: 2.1
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DOI: 10.2105/ajph.2021.306575
发表时间: 2022-02-01
影响因子: 12.7
作者:
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