Effects of abstinence from smoking on sleep and daytime sleepiness.
Effects of abstinence from smoking on sleep and daytime sleepiness.
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戒烟对睡眠和白天嗜睡的影响。
DOI：
10.1378/chest.105.4.1136
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发表时间：
1994
期刊：
影响因子：
9.6
通讯作者：
M. Dickel
中科院分区：
文献类型：
--
作者：
G. L. Prosise;Michael H. Bonnet;Richard B. Berry;M. Dickel
本研究调查了18名年龄在35 - 49岁之间、每天至少吸烟20支、持续2年以上的受试者（10名男性和8名女性）戒烟对睡眠质量、白天嗜睡和情绪的影响。适应之夜后，受试者连续两周接受研究。在第1周（研究第1、2和3晚），受试者照常吸烟。在第2周期间，从第4晚前3小时开始强制戒烟，并在第6晚最终检查后结束。每天晚上进行完整的睡眠监测，然后进行全天的多次睡眠潜伏期测试（MSLT）。在MSLT之间全天进行精神运动测试和情绪观察。将受试者吸烟时的测试结果与不吸烟的白天和夜晚的测试结果进行比较。第1晚和第4晚被认为是适应性夜晚，不包括在分析中。夜间研究显示，戒烟期间相对觉醒（从睡眠阶段到清醒、第1阶段睡眠或运动的变化）、阶段变化和觉醒的数量显著增加。在戒烟期间，第1阶段睡眠的MMP 3潜伏期减少。同样在禁欲期间，受试者报告说，他们感到更加易怒，焦虑感增加，感到更紧张，对香烟有更多的渴望。我们的结论是，戒烟与增加白天嗜睡和受损的情绪。白天嗜睡可能是由于睡眠障碍和通常通过吸烟提供的尼古丁戒断的结合。
This study examined the effect of smoking abstinence on sleep quality, daytime sleepiness, and mood in 18 subjects (10 men and 8 women) aged 35 to 49 years who had smoked at least 20 cigarettes per day for more than 2 years. Subjects were studied on two consecutive weeks following an adaptation night. During week 1 (study nights 1, 2, and 3), the subjects smoked as usual. Smoking abstinence was mandatory during week 2 beginning 3 h prior to night 4 and ending after the final tests on night 6. Complete sleep monitoring each night was followed by multiple sleep latency tests (MSLTs) throughout the day. Psychomotor tests and mood observations were performed throughout the day between the MSLTs. The results of testing when the subjects smoked were compared with those during nonsmoking days and nights. Nights 1 and 4 were considered adaptation nights and not included in the analysis. Overnight studies showed a significant increase in the number of relative arousals (a change in sleep stage to wake, stage 1 sleep, or movement), stage changes, and awakenings during smoking cessation. The MSLT latency to stage 1 sleep decreased during smoking cessation. Also during abstinence, the subjects reported that they felt more irritable, had increased feelings of anxiety, felt greater tension, and had more cravings for cigarettes. We conclude that smoking cessation is associated with increased daytime sleepiness and impaired mood. The daytime sleepiness may be due to the combination of sleep disturbance and withdrawal of the nicotine normally provided through smoking.
血液尼古丁、烟雾暴露和烟草戒断症状。
影响因子：
4.4
作者：
Hatsukami,DK;Hughes,JR;Pickens,RW
通讯作者：
Pickens,RW