Insight into a bad omen for white men: coronary artery disease--the Bogalusa Heart Study.
Insight into a bad omen for white men: coronary artery disease--the Bogalusa Heart Study.
复制标题
洞察白人的凶兆:冠状动脉疾病——博加卢萨心脏研究。
DOI:
10.1016/0002-9149(89)90681-4
复制
发表时间:
1989
期刊:
影响因子:
--
通讯作者:
Tracy,RE
中科院分区:
文献类型:
--
作者:
Berenson,GS;Srinivasan,SR;Wattigney,W;Webber,LS;Newman3rd,WP;Tracy,RE
Clinical experience of diagnostic and interventional procedures, including cardiac surgery, indicates a greater prevalence of coronary heart disease in white men than in other race-gender groups. Studies of children and young adults in the Bogalusa Heart Study have provided evidence that might account for this race-gender contrast. A variety of anthropometric and metabolic parameters influencing serum lipid and lipoprotein levels places white boys and young white men selectively at high risk for the development of atherosclerotic coronary artery disease. Obesity and greater central body fat, subtle aberrations in carbohydrate-lipid metabolic relations and variability in sex hormone profiles appear to underlie a trend to adverse lipoprotein changes in white men. A lower high-density lipoprotein cholesterol level and apolipoprotein A-I at puberty and a dramatic increase of low-density lipoprotein cholesterol are seen in young white men; such adverse changes identify them to be at greater risk. It is noteworthy that children whose fathers had myocardial infarction tend to be white. These children also have relatively high ratios of apolipo-protein B/apolipoprotein A-I and apolipoprotein B/ low-density lipoprotein cholesterol. Studies of risk factors in children emphasize their importance in the early natural history of coronary artery disease. These findings show the need for beginning prevention of adult heart disease in childhood.
登录
查看更多内容
DOI:
--
发表时间:
1979
期刊:
Metabolism: Clinical and Experimental
影响因子:
--
作者:
G. Berenson;A. Voors;L. Webber;E. Dalferes;D. Harsha
通讯作者:
D. Harsha
影响因子:
5.1
作者:
Voors,AW;Srinivasan,SR;Hunter,SM;Webber,LS;Sklov,MC;Berenson,GS
通讯作者:
Berenson,GS
DOI:
10.1097/00000441-198905000-00001
发表时间:
1989
期刊:
The American journal of the medical sciences
影响因子:
--
作者:
Soto,LF;Kikuchi,DA;Arcilla,RA;Savage,DD;Berenson,GS
通讯作者:
Berenson,GS
影响因子:
8
作者:
Srinivasan,SR;Freedman,DS;Sharma,C;Webber,LS;Berenson,GS
通讯作者:
Berenson,GS
影响因子:
12.7
作者:
L. Webber;S. Hunter;J. G. Baugh;S. Srinivasan;M. Sklov;G. Berenson
通讯作者:
G. Berenson