Ocular elongation and retraction in foveated reptiles
Ocular elongation and retraction in foveated reptiles
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中心凹爬行动物的眼球伸长和缩回
DOI：
10.1002/dvdy.348
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发表时间：
2021
影响因子：
2.5
通讯作者：
Lauderdale, James D.
中科院分区：
文献类型：
--
作者：
Rasys, Ashley M.;Pau, Shana H.;Irwin, Katherine E.;Luo, Sherry;Kim, Hannah Q.;Wahle, Margaret Austin;Trainor, Paul A.;Menke, Douglas B.;Lauderdale, James D.
背景在从人类到蜥蜴的许多物种中，观察到眼睛发育过程中眼球大小发生明显的不对称变化。相比之下，啮齿类动物等其他物种的地球大小在很大程度上是对称的变化。我们认为，发育中眼睛三维结构的不对称变化与产生高光感受器密度区域所需的视网膜重塑类型相关。为了验证这个想法，我们系统地研究了双孔棕色变色蜥蜴（Anolis sagrei）的眼球大小与眼睛发育函数的三维关系。结果在胚胎发育过程中，变色蜥蜴眼睛的眼睛形状发生动态变化。最初是球形的，眼睛在视网膜的假定中央凹区域拉长，然后经过一段回缩期，使眼睛恢复到球形。在此收缩期间，观察到凹坑形成和感光细胞堆积。我们发现了与遮盖变色龙（Chamaeleo calyptratus）的单个中央凹相关的类似的伸长和收缩模式。结论这些结果与其他中央凹物种的结果一起支持这样的观点，即在发育过程中眼球不对称伸长和收缩的区域中出现高光感受器堆积区域。
BackgroundPronounced asymmetric changes in ocular globe size during eye development have been observed in a number of species ranging from humans to lizards. In contrast, largely symmetric changes in globe size have been described for other species like rodents. We propose that asymmetric changes in the three‐dimensional structure of the developing eye correlate with the types of retinal remodeling needed to produce areas of high photoreceptor density. To test this idea, we systematically examined three‐dimensional aspects of globe size as a function of eye development in the bifoveated brown anole,Anolis sagrei.ResultsDuring embryonic development, the anole eye undergoes dynamic changes in ocular shape. Initially spherical, the eye elongates in the presumptive foveal regions of the retina and then proceeds through a period of retraction that returns the eye to its spherical shape. During this period of retraction, pit formation and photoreceptor cell packing are observed. We found a similar pattern of elongation and retraction associated with the single fovea of the veiled chameleon,Chamaeleo calyptratus.ConclusionsThese results, together with those reported for other foveated species, support the idea that areas of high photoreceptor packing occur in regions where the ocular globe asymmetrically elongates and retracts during development.
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影响因子：
4.2
作者：
Hendrickson A
通讯作者：
Hendrickson A
影响因子：
11.8
作者：
Infante CR;Mihala AG;Park S;Wang JS;Johnson KK;Lauderdale JD;Menke DB
通讯作者：
Menke DB
DOI：
--
发表时间：
--
期刊：
影响因子：
--
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S. Detwiler;H. Laurens
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H. Laurens
一种估计组织切片中细胞数量的方法。
DOI：
--
发表时间：
1965
期刊：
Journal of the Royal Microscopical Society
影响因子：
--
作者：
S. Ebbesson;D. Tang
通讯作者：
D. Tang
影响因子：
3
作者：
CLARKE, PGH
通讯作者：
CLARKE, PGH