Utilizing the power of Cerenkov light with nanotechnology.

Utilizing the power of Cerenkov light with nanotechnology.
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利用切伦科夫光的力量和纳米技术。

DOI:
10.1038/nnano.2016.301
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发表时间:
2017-02-07
影响因子:
38.3
通讯作者:
Grimm J
Grimm J
中科院分区:
材料科学1区
文献类型:
--
作者:
Shaffer TM;Pratt EC;Grimm J

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切伦科夫发光(CL)特有的蓝色辉光是由比光的相速度更快的带电粒子与介电介质(如水或组织)之间的相互作用产生的。由于CL有多种来源,如宇宙事件、粒子加速器、核反应堆和临床放射性核素,因此它已被用于粒子检测、剂量测定、医学成像和治疗等应用。氯离子与纳米颗粒的结合在生物医学上改善了诊断和治疗,特别是在肿瘤研究中。虽然放射性衰变本身不容易调节,但相关的CL可以通过使用纳米粒子来调节,从而在生物医学研究中提供了新的应用。纳米粒子、超材料和光子晶体的进展也产生了CL的新行为。本文综述了切伦科夫发光背后的物理学及其在生物医学中的相关应用。我们还表明,通过将纳米技术和材料科学的进步与CL相结合,为基础科学和应用科学开辟了新的途径。
The characteristic blue glow of Cerenkov luminescence (CL) arises from the interaction between a charged particle travelling faster than the phase velocity of light and a dielectric medium, such as water or tissue. As CL emanates from a variety of sources, such as cosmic events, particle accelerators, nuclear reactors and clinical radionuclides, it has been used in applications such as particle detection, dosimetry, and medical imaging and therapy. The combination of CL and nanoparticles for biomedicine has improved diagnosis and therapy, especially in oncological research. Although radioactive decay itself cannot be easily modulated, the associated CL can be through the use of nanoparticles, thus offering new applications in biomedical research. Advances in nanoparticles, metamaterials and photonic crystals have also yielded new behaviours of CL. Here, we review the physics behind Cerenkov luminescence and associated applications in biomedicine. We also show that by combining advances in nanotechnology and materials science with CL, new avenues for basic and applied sciences have opened.
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