A surface roughness comparison of cartilage in different types of synovial joints.
A surface roughness comparison of cartilage in different types of synovial joints.
复制标题
不同类型滑膜关节软骨表面粗糙度的比较。
DOI：
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复制
发表时间：
2012
期刊：
影响因子：
--
通讯作者：
R. Hanson
中科院分区：
文献类型：
--
作者：
P. A. Smyth;R. Rifkin;R. Jackson;R. Hanson
关节软骨的天然结构已被证明是促进马和其他动物关节运动和负荷支撑的有效手段。出于这个原因，软骨已经被广泛研究多年。尽管在多项研究中已经通过原子力显微镜（AFM）和其他方法确定了软骨的粗糙度，但尚未完成粗糙度与关节功能的比较。据推测，具有不同运动和润滑状态的各种关节类型改变了对关节面的需求，这可能影响软骨表面特性。从16只马前肢上采集腕骨软骨进行微纳米探针轮廓测量。采用Veeco Dektak 150 Stylus表面轮廓仪测量了取自三种不同功能关节类型（桡腕关节、腕中关节和腕掌关节）的80个软骨表面样本。每个关节的平均表面粗糙度测量值具有统计学差异。这表明软骨的结构适应于其操作环境或被其操作环境磨损。软骨微观和纳米级粗糙度的知识将有助于关节内物质或表面治疗的未来开发和设计，以保持关节完整性并减少关节性能的限制或损失。
The naturally occurring structure of articular cartilage has proven to be an effective means for the facilitation of motion and load support in equine and other animal joints. For this reason, cartilage has been extensively studied for many years. Although the roughness of cartilage has been determined from atomic force microscopy (AFM) and other methods in multiple studies, a comparison of roughness to joint function has not be completed. It is hypothesized that various joint types with different motions and regimes of lubrication have altered demands on the articular surface that may affect cartilage surface properties. Micro- and nanoscale stylus profilometry was performed on the carpal cartilage harvested from 16 equine forelimbs. Eighty cartilage surface samples taken from three different functioning joint types (radiocarpal, midcarpal, and carpometacarpal) were measured by a Veeco Dektak 150 Stylus Surface Profilometer. The average surface roughness measurements were statistically different for each joint. This indicates that the structure of cartilage is adapted to, or worn by, its operating environment. Knowledge of cartilage micro- and nanoscale roughness will assist the future development and design of treatments for intra- articular substances or surfaces to preserve joint integrity and reduce limitations or loss of joint performance.
DOI：
10.1115/1.1503795
发表时间：
2002-10-01
影响因子：
1.7
作者：
Wang, CCB;Deng, JM;Hung, CT
通讯作者：
Hung, CT
DOI：
10.1115/1.2768110
发表时间：
2007-10-01
影响因子：
1.7
作者：
Simha, Narendra K.;Jin, Hui;Lewis, Jack L.
通讯作者：
Lewis, Jack L.
影响因子：
2.4
作者：
Ateshian, Gerard A.
通讯作者：
Ateshian, Gerard A.