Rhinitis associated with pesticide use among private pesticide applicators in the agricultural health study.

Rhinitis associated with pesticide use among private pesticide applicators in the agricultural health study.
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DOI:
10.1080/15287394.2010.497443
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发表时间:
2010
期刊:
Journal of toxicology and environmental health. Part A
影响因子:
--
通讯作者:
Hoppin JA
Hoppin JA
中科院分区:
其他
文献类型:
--
作者:
Slager RE;Simpson SL;Levan TD;Poole JA;Sandler DP;Hoppin JA

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Farmers commonly experience rhinitis but the risk factors are not well-characterized. The aim of this study was to analyze cross-sectional data on rhinitis in the past year and pesticide use from 21,958 Iowa and North Carolina farmers in the Agricultural Health Study, enrolled 1993–7, to evaluate pesticide predictors of rhinitis. Polytomous and logistic regression models were used to assess association between pesticide use and rhinitis while controlling for demographics and farm-related exposures. Sixty-seven % of farmers reported current rhinitis and 39% reported three or more rhinitis episodes. The herbicides glyphosate [Odds Ratio (OR) = 1.09, 95% Confidence Interval (95% CI) = 1.05–1.13] and petroleum oil (OR = 1.12, 95% CI = 1.05–1.19) were associated with current rhinitis and increased rhinitis episodes. Of the insecticides, 4 organophosphates (chlorpyrifos, diazinon, dichlorvos, and malathion), carbaryl and use of permethrin on animals were predictors of current rhinitis. Diazinon was significant in the overall polytomous model and was associated with an elevated OR of 13+ rhinitis episodes (13+ episodes OR = 1.23, 95% CI = 1.09–1.38). The fungicide captan was also a significant predictor of rhinitis. Use of petroleum oil, malathion, permethrin and the herbicide metolachlor were significant in exposure-response polytomous models. Specific pesticides may contribute to rhinitis in farmers; agricultural activities did not explain these findings.
DOI: 10.1002/ajim.20018
发表时间: 2004-07-01
影响因子: 3.5
作者:
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发表时间: 2004-10-01
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