tartan underlies the evolution of male Drosophila genital morphology
tartan underlies the evolution of male Drosophila genital morphology
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格子呢是雄性果蝇生殖器形态进化的基础
DOI：
10.1101/462259
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发表时间：
2018
期刊：
影响因子：
--
通讯作者：
Hagen J
中科院分区：
文献类型：
--
作者：
Hagen J
雄性生殖器结构是进化最快的形态特征之一，通常是唯一可以区分密切相关物种的特征。这一过程被认为是由性选择驱动的，可能会加强物种分离。然而，虽然许多表型差异的遗传基础已经确定，我们仍然缺乏对男性生殖器官和器官大小更普遍的进化差异的基因的知识。抱茎器（surstyli）是一种在昆虫交配过程中起重要作用的外周结构。在这里，我们表明，自然变异的抱器大小和刚毛数量之间的果蝇mauritiana和D。simulansis由intartan（trn）的进化变化引起，其编码介导细胞间相互作用和亲和力差异的跨膜富含亮氨酸的重复结构域蛋白。D之间没有固定的氨基酸差异。mauritiana和D.但该基因在发育中的生殖器中的表达差异表明，顺式调节变化是这些物种中抱器形态进化的内在基础。最后，分析基因相同的相互半合子，除了trn的功能等位基因来自哪个物种，确定D. mauritianasspecifies较大的抱茎，比D的等位基因具有更多的刚毛。simulans。因此，我们已经确定了第一个基因背后的进化变化的大小的男性生殖器官，这将有助于更好地了解这些结构的快速多样化和调节和进化的器官大小更广泛。意义声明男性生殖器官的形态进化迅速性选择驱动。然而，人们对物种之间生殖器差异背后的基因知之甚少。识别这些基因是理解性选择如何作用于发育以产生快速表型变化的关键。我们发现，雄性毛里求斯果蝇和D. simulansin的大小和刚毛数量的抱器-生殖器的突出，抓住女性在交配。此外，由于artan编码一种参与细胞亲和性的蛋白质，这可能代表了形态变化的一种新的发育机制。因此，我们的研究为男性生殖器和器官大小的快速进化提供了新的遗传和发育基础。
Male genital structures are among the most rapidly evolving morphological traits and are often the only features that can distinguish closely related species. This process is thought to be driven by sexual selection and may reinforce species separation. However, while the genetic basis of many phenotypic differences have been identified, we still lack knowledge about the genes underlying evolutionary differences in male genital organs and organ size more generally. The claspers (surstyli) are periphallic structures that play an important role in copulation in insects. Here we show that natural variation in clasper size and bristle number betweenDrosophila mauritianaandD. simulansis caused by evolutionary changes intartan (trn), which encodes a transmembrane leucine-rich repeat domain protein that mediates cell-cell interactions and affinity differences. There are no fixed amino acid differences intrnbetweenD. mauritianaandD. simulansbut differences in the expression of this gene in developing genitalia suggest cis-regulatory changes intrnunderlie the evolution of clasper morphology in these species. Finally, analysis of reciprocal hemizyotes that are genetically identical, except for which species the functional allele oftrnis from, determined that thetrnallele ofD. mauritianaspecifies larger claspers with more bristles than the allele ofD. simulans. Therefore we have identified the first gene underlying evolutionary change in the size of a male genital organ, which will help to better understand the rapid diversification of these structures and the regulation and evolution of organ size more broadly.Significance StatementThe morphology of male genital organs evolves rapidly driven by sexual selection. However, little is known about the genes underlying genitalia differences between species. Identifying these genes is key to understanding how sexual selection acts on development to produce rapid phenotypic change. We have found that the genetartanunderlies differences between maleDrosophila mauritianaandD. simulansin the size and bristle number of the claspers - genital projections that grasp the female during copulation. Moreover, sincetartanencodes a protein that is involved in cell affinity, this may represent a new developmental mechanism for morphological change. Therefore, our study provides new insights into genetic and developmental bases for the rapid evolution of male genitalia and organ size more generally.
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影响因子：
3.3
作者：
COYNE, JA
通讯作者：
COYNE, JA
个体遗传对模拟果蝇和毛里求斯果蝇生殖器形状变异的贡献
DOI：
--
发表时间：
2014
期刊：
International Journal of Evolutionary Biology
影响因子：
--
作者：
Hélène LeVasseur;A. Moehring
通讯作者：
A. Moehring
影响因子：
3.3
作者：
Jianjun Liu;John M. Mercer;L. F. Stam;Gregory C. Gibson;Zhao-Bang Zeng;Cathy C. Laurie
通讯作者：
Jianjun Liu;John M. Mercer;L. F. Stam;Gregory C. Gibson;Zhao-Bang Zeng;Cathy C. Laurie
果蝇物种复合体的交配不对称性和系统发育
DOI：
--
发表时间：
1988
期刊：
影响因子：
--
作者：
H. Robertson
通讯作者：
H. Robertson
影响因子：
3.3
作者：
Zhao-Bang Zeng;Jianjun Liu;L. F. Stam;C. Kao;J. Mercer;C. Laurie
通讯作者：
Zhao-Bang Zeng;Jianjun Liu;L. F. Stam;C. Kao;J. Mercer;C. Laurie