Sociodemographic and clinical characteristics of treated and untreated adults with bulimia nervosa or binge-eating disorder recruited for a large-scale research study.
Sociodemographic and clinical characteristics of treated and untreated adults with bulimia nervosa or binge-eating disorder recruited for a large-scale research study.
复制标题
DOI：
10.1186/s40337-023-00846-4
复制
发表时间：
2023-07-31
影响因子：
4.1
通讯作者：
Watson, Hunna J. J.
中科院分区：
文献类型：
--
作者：
Carrino, Emily A. A.;Flatt, Rachael E. E.;Pawar, Pratiksha S. S.;Sanzari, Christina M. M.;Tregarthen, Jenna P. P.;Argue, Stuart;Thornton, Laura M. M.;Bulik, Cynthia M. M.;Watson, Hunna J. J.
关键词：
饮食失调影响着全世界数百万人，但大多数人从未接受过治疗。大多数关于饮食失调的临床研究都集中在从治疗环境中招募的个体上，这可能不代表更广泛的饮食失调人群。本研究旨在根据进食障碍患者是否自我报告接受治疗来确定其特征的潜在差异，以便更好地了解他们的不同需求和经历。研究人群包括762名社区招募的个体（85%女性，M ± SD，年龄= 30 ± 7岁）患有神经性贪食症或暴食症（BN/BED）的参与者参加了暴食遗传学倡议（开始）美国研究组。参与者完成了关于人口统计学、治疗史、过去和现在的饮食失调症状、体重史、以及他们目前的心理健康和胃肠道症状。未接受治疗的参与者（n = 291，38%）与接受治疗的参与者（n = 471，62%）进行了比较，这些参与者自我报告在生活中的某个时候接受BN/BED治疗。与接受治疗的参与者相比，未接受治疗的参与者不成比例地自我认同为男性和少数种族或民族。接受治疗的参与者报告了更严重的病史，具体而言，发病年龄更早，一生中更长期和频繁的饮食失调症状，以及更大的身体不满和共病心理健康症状（即，抑郁症、焦虑症、多动症）。神经性厌食症病史与治疗参与呈正相关。自我报告住院或住院治疗史的个人表现出最严重的病史，门诊治疗的人有较轻的病史，未经治疗的人有最轻的病史。历史上被忽视和边缘化的人群自我报告的治疗获得率较低，而那些获得治疗的人报告了更严重的饮食失调和共病的心理健康症状，这可能促使他们寻求治疗。基于临床的招募样本可能不代表症状较轻或种族和民族多样性的个体以及男性。基于社区的招聘对于提高将研究成果应用于更广泛人群的能力和减少医学研究中的差异至关重要。试验注册ClinicalTrials.gov NCT 04162574（https：//clinicaltrials.gov/ct2/show/NCT04162574）。在线版本包含补充材料，可通过10.1186/s40337-023-00846-4获得。大多数患有饮食失调症的人从未接受过治疗。然而，大多数关于饮食失调的临床研究都从诊所和治疗中心招募参与者。因此，我们对饮食失调的大部分了解可能并不代表大多数饮食失调患者，特别是那些没有接受治疗的人。我们从社区招募了762名神经性贪食症或暴食症患者参加一项大型研究。我们比较了从未接受过治疗的参与者（38%）和在生活中某个时候接受过治疗的参与者（62%）。与接受过治疗的参与者（主要是女性和白色）相比，未接受治疗的参与者更有可能被认为是男性和种族或少数民族。接受治疗的参与者在研究时有更严重的病史和更高水平的身体不满和心理健康症状。本研究强调了从社区招募研究参与者进行临床研究的重要性，以此来解决边缘化和代表性不足群体的医疗不平等问题。此外，在将研究结果从寻求治疗的研究样本推广到所有饮食失调患者时，应谨慎。在线版本包含补充材料，可通过10.1186/s40337-023-00846-4获得。
Eating disorders affect millions of people worldwide, but most never receive treatment. The majority of clinical research on eating disorders has focused on individuals recruited from treatment settings, which may not represent the broader population of people with eating disorders. This study aimed to identify potential differences in the characteristics of individuals with eating disorders based on whether they self-reported accessing treatment or not, in order to contribute to a better understanding of their diverse needs and experiences. The study population included 762 community-recruited individuals (85% female, M ± SD age = 30 ± 7 years) with bulimia nervosa or binge-eating disorder (BN/BED) enrolled in the Binge Eating Genetics Initiative (BEGIN) United States study arm. Participants completed self-report surveys on demographics, treatment history, past and current eating disorder symptoms, weight history, and their current mental health and gastrointestinal symptoms. Untreated participants (n = 291, 38%) were compared with treated participants (n = 471, 62%) who self-reported accessing BN/BED treatment at some point in their lives. Untreated participants disproportionately self-identified as male and as a racial or ethnic minority compared with treated participants. Treated participants reported a more severe illness history, specifically, an earlier age at onset, more longstanding and frequent eating disorder symptoms over their lifetime, and greater body dissatisfaction and comorbid mental health symptoms (i.e., depression, anxiety, ADHD) at the time of the study. A history of anorexia nervosa was positively associated with treatment engagement. Individuals self-reporting a history of inpatient or residential treatment exhibited the most severe illness history, those with outpatient treatment had a less severe illness history, and untreated individuals had the mildest illness history. Historically overlooked and marginalized populations self-reported lower treatment access rates, while those who accessed treatment reported more severe eating disorder and comorbid mental health symptoms, which may have motivated them to seek treatment. Clinic-based recruitment samples may not represent individuals with milder symptoms or racial and ethnic diversity, and males. Community-based recruitment is crucial for improving the ability to apply research findings to broader populations and reducing disparities in medical research. Trial Registration ClinicalTrials.gov NCT04162574 (https://clinicaltrials.gov/ct2/show/NCT04162574). The online version contains supplementary material available at 10.1186/s40337-023-00846-4. The majority of individuals with eating disorders never enter treatment. However, most clinical research on eating disorders recruits participants from clinics and treatment centers. Therefore, most of our knowledge about eating disorders may not represent the majority of people with eating disorders, particularly those who do not enter treatment. We studied 762 people with bulimia nervosa or binge-eating disorder recruited from the community to a large research study. We compared participants who reported never accessing treatment (38%) to participants who reported having accessed treatment at some point in their lives (62%). Untreated participants were much more likely to identify as male and as a racial or ethnic minority compared with participants who had accessed treatment (who identified mostly as female and White). Participants who had accessed treatment had a more severe illness history and higher levels of body dissatisfaction and mental health symptoms at the time of the study. The present study highlights the importance of recruiting research participants from the community to clinical studies as a way to address medical inequity in marginalized and underrepresented groups. Additionally, caution is advised when generalizing research findings from research samples who have sought treatment to all people with eating disorders. The online version contains supplementary material available at 10.1186/s40337-023-00846-4.
登录
查看更多内容
影响因子：
4.4
作者：
Bulik, Cynthia M.;Butner, Jonathan E.;Deboeck, Pascal R.
通讯作者：
Deboeck, Pascal R.
影响因子：
4.1
作者：
Ljotsson, B.;Lundin, C.;Ghaderi, A.
通讯作者：
Ghaderi, A.
影响因子：
3.8
作者：
Johnson, Sverre Urnes;Ulvenes, Pal Gunnar;Hoffart, Asle
通讯作者：
Hoffart, Asle
影响因子：
5.5
作者：
Becker, AE;Franko, DL;Herzog, DB
通讯作者：
Herzog, DB
DOI：
10.1111/j.1443-9573.2006.00265.x
发表时间：
2006-01-01
期刊：
Chinese journal of digestive diseases
影响因子：
--
作者：
Drossman, Douglas A
通讯作者：
Drossman, Douglas A