Pulsed dye laser (577 nm) treatment of portwine stains: ultrastructural evidence of neovascularization and mast cell degranulation in healed lesions.
Pulsed dye laser (577 nm) treatment of portwine stains: ultrastructural evidence of neovascularization and mast cell degranulation in healed lesions.
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脉冲染料激光（577 nm）治疗鲜红斑：愈合病变中新生血管形成和肥大细胞脱颗粒的超微结构证据。
DOI：
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发表时间：
1988
影响因子：
6.5
通讯作者：
G. Murphy
中科院分区：
文献类型：
--
作者：
O. Tan;D. Whitaker;J. Garden;G. Murphy
使用超微结构技术，在脉冲染料激光（577 nm）成功清除之前、之后和之后 1 年对葡萄酒染色进行了检查。治疗前病变皮肤的特征是血管通道扩张和肥大细胞发育不全。治疗后立即观察到广泛的选择性血管坏死，类似于之前描述的变化。激光照射一年后，异常扩张的鲜红斑痣血管被小静脉和小动脉取代，其数量和直径与正常皮肤的血管相似；唯一注意到的区别是这些新血管被易于识别的肥大细胞包围。许多肥大细胞表现出活化和脱粒的证据。我们得出的结论是，肥大细胞可能在 577 nm 染料激光照射处理的鲜红斑痣的新血管形成中发挥重要作用。
Portwine stains were examined before, immediately after, and 1 yr after successful clearance by a pulsed dye laser (577 nm) using ultrastructural techniques. Dilated vascular channels and mast cell hypoplasia characterized lesional skin before treatment. Immediately after treatment, widespread selective vessel necrosis, similar to changes previously described, was observed. One year after laser irradiation, the abnormally ectatic portwine stain vessels had been replaced by small venules and arterioles, similar in number and diameter to blood vessels in normal skin; the only difference noted was that these new vessels were surrounded by easily identifiable mast cells. Many of these mast cells exhibited evidence of activation and degranulation. We conclude that mast cells may play an important role in the neovascularization of portwine stains treated by 577-nm dye laser irradiation.
皮肤温度对脉冲激光照射引起的选择性血管损伤的影响。
DOI：
10.1111/1523-1747.ep12277154
发表时间：
1985
期刊：
The Journal of investigative dermatology
影响因子：
--
作者：
Tan,OT;Kerschmann,R;Parrish,JA
通讯作者：
Parrish,JA