One-year postpartum outcomes following a weight management intervention in pregnant women with obesity.

One-year postpartum outcomes following a weight management intervention in pregnant women with obesity.
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DOI:
10.1002/oby.21597
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发表时间:
2016-10
期刊:
影响因子:
6.9
通讯作者:
Stevens, Victor J.
Stevens, Victor J.
中科院分区:
医学2区
文献类型:
--
作者:
Vesco, Kimberly K.;Leo, Michael C.;Karanja, Njeri;Gillman, Matthew W.;McEvoy, Cindy T.;King, Janet C.;Eckhardt, Cara L.;Smith, K. Sabina;Perrin, Nancy;Stevens, Victor J.

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这项分析的重点是一项随机试验的1年母婴随访,该试验测试了妊娠期间进行的体重管理干预。我们将114名平均妊娠15周的肥胖妇女(平均BMI 36.7 kg/m2)随机分配到体重管理干预组或常规护理控制组。干预在分娩时结束,与对照组相比,干预组的妊娠期体重增加较少,胎龄较大的新生儿比例较低。产后12个月的主要结局是母亲体重。次要结局包括婴儿年龄别体重和身长别体重z评分。1年时,干预组的母亲体重为96.3±18.6 kg,对照组为99.7±19.2 kg。两组从随机化至产后1年的体重变化无显著差异(B=-0.47,95% CI [-4.03,3.08])。婴儿年龄别体重z评分(B=-0.40,95% CI [-0.75,-0.05])有显著的组主效应,但婴儿身长别体重z评分无显著主效应(B=-0.20,95% CI [-0.59,0.20])。妊娠期体重管理干预并不影响产妇体重或婴儿体重的长度在产后1年。未来的研究可能是必要的,以确定是否延长产前干预到产后期间将有利于产妇和婴儿的结果。
This analysis focuses on 1-year maternal and infant follow-up of a randomized trial that tested a weight management intervention conducted during pregnancy. We randomly assigned 114 women with obesity (mean BMI 36.7 kg/m2) at a mean of 15 weeks’ gestation to a weight management intervention or usual care control condition. The intervention ended at delivery and resulted in less gestational weight gain and a lower proportion of large-for-gestational age newborns among intervention compared to control participants. The primary outcome at 12 months postpartum was maternal weight. Secondary outcomes included infant weight-for-age and weight-for-length z-scores. At 1 year, mothers in the intervention group weighed 96.3±18.6 kg, and in the control group, 99.7±19.2 kg. There was no significant difference between groups in change in weight from randomization to 1-year postpartum (b=-0.47, 95% CI [-4.03, 3.08]. There was a significant main effect of group for infant weight-for-age z-score (b=-0.40, 95% CI [-0.75,-0.05]) but not infant weight-for-length z-scores (b=-0.20, 95% CI [-0.59,0.20]. A gestational weight management intervention did not influence maternal weight or infant weight-for-length at 1-year postpartum. Future studies may be warranted to determine if extending prenatal interventions into the postpartum period would be beneficial for maternal and infant outcomes.
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作者:
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通讯作者: Stevens, Victor J.