Missed Opportunities for Adolescent Immunizations at Well-Care Visits During the COVID-19 Pandemic.

Missed Opportunities for Adolescent Immunizations at Well-Care Visits During the COVID-19 Pandemic.
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DOI:
10.1016/j.jadohealth.2023.05.008
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发表时间:
2023-09
影响因子:
7.6
通讯作者:
Fiks, Alexander G.
Fiks, Alexander G.
中科院分区:
医学2区
文献类型:
--
作者:
Kelly, Mary Kate;Stephens-Shields, Alisa J.;Hannan, Chloe;Rand, Cynthia M.;Localio, Russell;Shone, Laura P.;Steffes, Jennifer;Davis, Kristin;Grundmeier, Robert W.;Humiston, Sharon G.;Albertin, Christina;Mcfarland, Greta;Abney, Dianna E.;Szilagyi, Peter G.;Fiks, Alexander G.

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2019年冠状病毒病大流行扰乱了医疗保健,但对疫苗接种错失机会(MO,未接种疫苗而符合疫苗资格的就诊)的影响尚不清楚。我们评估了三种疫苗:人乳头瘤病毒;四价脑膜炎球菌结合物;以及破伤风、白喉和无细胞百日咳(Tdap)疫苗在青少年良好护理访问中与大流行相关的趋势。我们分析了2018年1月1日至2021年12月31日期间13个州的24家儿科初级保健诊所的电子健康记录数据。分段Logistic回归估计了大流行期间MOS相对于流行前趋势的风险差异。在106,605次良好护理访问中,我们观察到所有三种疫苗流行前的MOS减少,而在大流行期间MOS增加。与流行前相比,人乳头瘤病毒(+15.9%,95%可信区间:11.7%,20.1%)、脑膜炎球菌结合物(+9.4%,95%可信区间:5.2%,13.7%)、破伤风、白喉和无细胞性百日咳(+8.2%,95%可信区间:4.3%,12.1%)的MOS增加。大流行期间疫苗MOS的增加等于或超过了大流行前的减少。减少青少年保健中的MO可以提高疫苗覆盖率。
The Coronavirus Disease 2019 pandemic disrupted healthcare, but the impact on vaccination missed opportunities (MOs, vaccine-eligible visits without vaccination) is unknown. We evaluated pandemic-related trends in MOs at adolescent well-care visits for three vaccines: human papillomavirus; quadrivalent meningococcal conjugate; and tetanus, diphtheria, and acellular pertussis (Tdap). We analyzed electronic health record data from 24 pediatric primary care practices in 13 states from 1/1/2018 to 12/31/2021. Segmented logistic regression estimated risk differences for MOs during the pandemic relative to prepandemic trends. Among 106,605 well-care visits, we observed decreases in MOs prepandemic followed by an increase in MOs during the pandemic for all three vaccines. Relative to prepandemic, MOs increased for human papillomavirus (+15.9%, 95% confidence interval [CI]: 11.7%, 20.1%), meningococcal conjugate (+9.4%, 95% CI: 5.2%, 13.7%), and tetanus, diphtheria, and acellular pertussis (Tdap) (+ 8.2%, 95% CI: 4.3%, 12.1%). Increases in vaccine MOs during the pandemic equaled or exceeded pre-pandemic decreases. Reducing MOs in adolescent well-care could raise vaccine coverage.
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