Protection against Influenza Virus Infection of Mice Fed Bifidobacterium breve YIT4064
Protection against Influenza Virus Infection of Mice Fed Bifidobacterium breve YIT4064
复制标题
喂养短双歧杆菌 YIT4064 的小鼠免受流感病毒感染的保护
DOI：
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发表时间：
1999
期刊：
影响因子：
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通讯作者：
K. Shida
中科院分区：
文献类型：
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作者：
H. Yasui;Junko Kiyoshima;Tetuji Hori;K. Shida
摘要 喂食短双歧杆菌 YIT4064 并口服流感病毒免疫的小鼠比仅接种流感病毒的小鼠能更有效地预防下呼吸道流感病毒感染。口服短双歧杆菌YIT4064并口服流感病毒免疫后，血清中抗流感病毒免疫球蛋白G（IgG）增强的小鼠数量明显多于仅口服流感病毒口服免疫的小鼠。这些发现表明，口服短双歧杆菌 YIT4064 可以增加血清中的抗流感病毒 IgG 抗体，并防止流感病毒感染。口服短双歧杆菌 YIT4064 可以增强针对口服各种致病抗原的抗原特异性 IgG，并诱导针对各种病毒感染的保护。
ABSTRACT Mice fed Bifidobacterium breve YIT4064 and immunized orally with influenza virus were more strongly protected against influenza virus infection of the lower respiratory tract than ones immunized with influenza virus only. The number of mice with enhanced anti-influenza virus immunoglobulin G (IgG) in serum upon oral administration of B. breve YIT4064 and oral immunization with influenza virus was significantly greater than that upon oral immunization with influenza virus only. These findings demonstrated that the oral administration of B. breve YIT4064 increased anti-influenza virus IgG antibodies in serum and protected against influenza virus infection. The oral administration of B. breve YIT4064 may enhance antigen-specific IgG against various pathogenic antigens taken orally and induce protection against various virus infections.
小鼠对活流感病毒和灭活流感病毒的肺和血清同种型抗体反应。
DOI：
10.1164/arrd.1986.134.1.6
发表时间：
1986
期刊：
The American review of respiratory disease
影响因子：
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作者：
Balkovic,ES;Six,HR
通讯作者：
Six,HR