Pathogenicity and virulence of Marburg virus.
Pathogenicity and virulence of Marburg virus.
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DOI:
10.1080/21505594.2022.2054760
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发表时间:
2022-12
期刊:
影响因子:
5.2
通讯作者:
Hassan MM
中科院分区:
文献类型:
--
作者:
Abir MH;Rahman T;Das A;Etu SN;Nafiz IH;Rakib A;Mitra S;Emran TB;Dhama K;Islam A;Siyadatpanah A;Mahmud S;Kim B;Hassan MM
Marburg virus (MARV) has been a major concern since 1967, with two major outbreaks occurring in 1998 and 2004. Infection from MARV results in severe hemorrhagic fever, causing organ dysfunction and death. Exposure to fruit bats in caves and mines, and human-to-human transmission had major roles in the amplification of MARV outbreaks in African countries. The high fatality rate of up to 90% demands the broad study of MARV diseases (MVD) that correspond with MARV infection. Since large outbreaks are rare for MARV, clinical investigations are often inadequate for providing the substantial data necessary to determine the treatment of MARV disease. Therefore, an overall review may contribute to minimizing the limitations associated with future medical research and improve the clinical management of MVD. In this review, we sought to analyze and amalgamate significant information regarding MARV disease epidemics, pathophysiology, and management approaches to provide a better understanding of this deadly virus and the associated infection.
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DOI:
10.1016/j.jbc.2021.100796
发表时间:
2021-01
期刊:
The Journal of biological chemistry
影响因子:
--
作者:
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通讯作者:
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影响因子:
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作者:
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通讯作者:
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Nlooto, Manimbulu
影响因子:
2.2
作者:
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DOI:
10.3390/v13122394
发表时间:
2021-11-30
期刊:
Viruses
影响因子:
--
作者:
Amman BR;Schuh AJ;Albariño CG;Towner JS
通讯作者:
Towner JS