Complications in COVID-19 patients: Characteristics of pulmonary embolism.

Complications in COVID-19 patients: Characteristics of pulmonary embolism.
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COVID-19患者的并发症:肺栓塞的特征。

DOI:
10.1016/j.clinimag.2021.05.016
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发表时间:
2021-09
期刊:
影响因子:
2.1
通讯作者:
Saba L
Saba L
中科院分区:
医学4区
文献类型:
--
作者:
Cau R;Pacielli A;Fatemeh H;Vaudano P;Arru C;Crivelli P;Stranieri G;Suri JS;Mannelli L;Conti M;Mahammedi A;Kalra M;Saba L

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本研究旨在评价疑似肺栓塞行CTA的COVID-19患者的胸部CT影像特征、临床特征及实验室价值。我们还研究了临床、实验室或放射学特征是否与较高的PE率有关。这项回顾性研究包括84例连续实验室确诊的SARS-CoV-2患者,他们因疑似PE接受了CTA检查。检查所有患者的PE的存在和定位以及胸部CT检查中肺混浊的类型和范围,并将其与合并症和实验室值的信息相关联。84例患者中有24例发现肺栓塞。我们观察到87%的PE发生在COVID-19肺炎的肺实质。与无PE患者相比,PE患者总体上表现出更大的肺实变(p = 0.02)和GGO (p < 0.01),以及更高水平的d -二聚体(p < 0.01)。PE组饱和度较低(p = 0.01),住院时间较长(p < 0.01)。我们的研究显示,在COVID-19肺炎中PE的发生率很高。与非PE患者相比,87%的患者在COVID-19肺炎的肺实质中发现PE, CT严重程度评分更差,肺大叶受累的数量更多。CT严重程度,饱和度降低,d -二聚体水平升高可能是CTPA的迹象。胸部非对比CT的某些表现可能是CTPA的指征。
The purpose of this study is to evaluate chest CT imaging features, clinical characteristics, laboratory values of COVID-19 patients who underwent CTA for suspected pulmonary embolism. We also examined whether clinical, laboratory or radiological characteristics could be associated with a higher rate of PE. This retrospective study included 84 consecutive patients with laboratory-confirmed SARS-CoV-2 who underwent CTA for suspected PE. The presence and localization of PE as well as the type and extent of pulmonary opacities on chest CT exams were examined and correlated with the information on comorbidities and laboratory values for all patients. Of the 84 patients, pulmonary embolism was discovered in 24 patients. We observed that 87% of PE was found to be in lung parenchyma affected by COVID-19 pneumonia. Compared with no-PE patients, PE patients showed an overall greater lung involvement by consolidation (p = 0.02) and GGO (p < 0.01) and a higher level of D-Dimer (p < 0,01). Moreover, the PE group showed a lower level of saturation (p = 0,01) and required more hospitalization (p < 0,01). Our study showed a high incidence of PE in COVID-19 pneumonia. In 87% of patients, PE was found in lung parenchyma affected by COVID-19 pneumonia with a worse CT severity score and a greater number of lung lobar involvement compared with non-PE patients. CT severity, lower level of saturation, and a rise in D-dimer levels could be an indication for a CTPA. Certain findings of non-contrast chest CT could be an indication for a CTPA.
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