A randomized clinical trial of prolonged exposure and applied relaxation for the treatment of Latinos with posttraumatic stress disorder.
A randomized clinical trial of prolonged exposure and applied relaxation for the treatment of Latinos with posttraumatic stress disorder.
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DOI：
10.1002/jts.22773
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发表时间：
2022-04
影响因子：
3.3
通讯作者：
Hembree, Elizabeth A.
中科院分区：
文献类型：
--
作者：
Vera, Mildred;Oben, Adriana;Juarbe, Deborah;Hernandez, Norberto;Kichic, Rafael;Hembree, Elizabeth A.
强有力的证据支持使用延长暴露疗法（PE）作为创伤后应激障碍（PTSD）的一线治疗。然而，拉丁美洲人并没有从PTSD治疗的进步中平等受益，并继续面临接受治疗的障碍。有共识认为，有必要支持扩大高质量的文化和语言上适当的治疗，以解决种族和少数民族在行为卫生保健方面所经历的差异。目前的研究是一项随机对照试验，在波多黎各讲西班牙语的拉丁裔PTSD患者中比较文化适应的PE干预与应用放松（AR）。合格的参与者（N = 98）被随机分配到PE（n = 49）或AR（n = 49）。两种治疗均包括每周12-15次治疗，每次持续60-90分钟。在基线、治疗后和3个月随访时，使用DSM-5的临床医生-管理员PTSD量表评估主要结局（临床医生评定的PTSD症状严重程度）。使用患者健康问卷和状态-特质焦虑量表评估次要结局。结果显示，治疗对PTSD症状具有较大的组内效应，PE：d = 1.29，95% CI [1.12，2.05]; AR：d = 1.38，95% CI [1.21，2.19]。组间对PTSD症状的影响较小，d =-0.09，95%CI [-0.48，0.31]。两种治疗条件下的参与者报告PTSD症状从基线到随访显著减少;此外，观察到抑郁和焦虑症状的组内显著减少。这些发现强调了PE和AR治疗西班牙语拉丁裔PTSD的潜在益处。
Robust evidence supports the use of prolonged exposure therapy (PE) as a first-line treatment for posttraumatic stress disorder (PTSD). However, Latinos have not benefitted equally from advancements in the treatment of PTSD and continue to face barriers to receiving care. There is consensus that it is necessary to support the expansion of high-quality culturally and linguistically appropriate treatment to address disparities experienced by racial and ethnic minorities in behavioral health care. The current study was a randomized controlled trial comparing a culturally adapted PE intervention with applied relaxation (AR) among Spanish-speaking Latinos with PTSD in Puerto Rico. Eligible participants (N = 98) were randomly assigned to PE (n = 49) or AR (n = 49). Both treatments included 12–15 weekly sessions each lasting 60–90 min. The primary outcome, clinician-rated PTSD symptom severity, was assessed using the Clinician-Administered PTSD Scale for DSM-5 at baseline, posttreatment, and 3-month follow-up. Secondary outcomes were assessed using the Patient Health Questionnaire and State–Trait Anxiety Inventory. Results showed a large within-group effect of treatment on PTSD symptoms, PE: d = 1.29, 95% CI [1.12, 2.05]; AR: d = 1.38, 95% CI [1.21, 2.19]. The between-group effect on PTSD symptoms was small, d = −0.09, 95% CI [−0.48, 0.31]. Participants in both treatment conditions reported significant decreases in PTSD symptoms from baseline to follow-up; additionally, significant within-group reductions in depression and anxiety symptoms were observed. These findings underscore the potential benefit of PE and AR for the treatment of Spanish-speaking Latinos with PTSD.
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影响因子：
5.9
作者：
Barrera, Manuel, Jr.;Castro, Felipe G.;Strycker, Lisa A.;Toobert, Deborah J.
通讯作者：
Toobert, Deborah J.
影响因子：
2.6
作者：
Kazlauskas, Evaldas
通讯作者：
Kazlauskas, Evaldas
影响因子：
9.7
作者：
Alegria, Margarita;Alvarez, Kiara;McPeck, Samantha
通讯作者：
McPeck, Samantha
影响因子：
7.4
作者：
Aponte-Rivera, Vivianne;Dunlop, Boadie W.;Ramirez, Cynthia;Kelley, Mary E.;Schneider, Rebecca;Blastos, Beatriz;Larson, Jacqueline;Mercado, Flavia;Mayberg, Helen;Craighead, W. Edward
通讯作者：
Craighead, W. Edward
影响因子：
4.1
作者：
Hinton, Devon E.;Hofmann, Stefan G.;Pollack, Mark H.
通讯作者：
Pollack, Mark H.