A new era for executive function research: On the transition from centralized to distributed executive functioning.

A new era for executive function research: On the transition from centralized to distributed executive functioning.
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DOI:
10.1016/j.neubiorev.2021.02.011
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发表时间:
2021-05
影响因子:
8.2
通讯作者:
Markett S
Markett S
中科院分区:
医学1区
文献类型:
--
作者:
Zink N;Lenartowicz A;Markett S

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“执行功能”(EFS)是较高的认知控制功能(例如工作记忆,抑制和认知灵活性)的伞,这在这一研究领域中最挑战的问题之一是解释了在没有全能但无形的中心行政机构的情况下,将其作为EFS的广泛认知过程。突破性地理解大脑如何控制和调节自身。将EF重新构成与高度分布的大脑过程的新兴后果,这些过程与高度连接的集线器区域进行交流,从而使中央执行人员的需求进一步讨论了对大脑驱动的大脑分析的需求。通过提供新的,可检验的假设并解决EF文献中的经验和理论不一致,可以和帮助我们对EF基本机制的理解。
“Executive functions” (EFs) is an umbrella term for higher cognitive control functions such as working memory, inhibition, and cognitive flexibility. One of the most challenging problems in this field of research has been to explain how the wide range of cognitive processes subsumed as EFs are controlled without an all-powerful but ill-defined central executive in the brain. Efforts to localize control mechanisms in circumscribed brain regions have not led to a breakthrough in understanding how the brain controls and regulates itself. We propose to re-conceptualize EFs as emergent consequences of highly distributed brain processes that communicate with a pool of highly connected hub regions, thus precluding the need for a central executive. We further discuss how graph-theory driven analysis of brain networks offers a unique lens on this problem by providing a reference frame to study brain connectivity in EFs in a holistic way and helps to refine our understanding of the mechanisms underlying EFs by providing new, testable hypotheses and resolves empirical and theoretical inconsistencies in the EF literature.
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