Adhesion Molecule CD146 and its Soluble Form Correlate Well with Carotid Atherosclerosis and Plaque Instability

Adhesion Molecule CD146 and its Soluble Form Correlate Well with Carotid Atherosclerosis and Plaque Instability
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粘附分子 CD146 及其可溶形式与颈动脉粥样硬化和斑块不稳定密切相关

DOI:
10.1111/cns.12234
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发表时间:
2014-05
影响因子:
5.5
通讯作者:
Yan, Xi-Yun
Yan, Xi-Yun
中科院分区:
医学1区
文献类型:
--
作者:
Feng, Li-Qun;Bi, Qi;Wang, Yong-Jun;Yan, Xi-Yun

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斑块内新生血管和泡沫细胞浸润有助于不稳定斑块的发展,导致血栓栓塞和中风。细胞粘附分子(CAM)已被报道参与动脉粥样硬化和斑块易损性的进展。本研究的目的是评估粘附分子CD 146与颈动脉斑块不稳定性的关系。
Intraplaque neovascularization and foam cell infiltration contribute to the development of unstable plaque, leading to thromboembolism and stroke. Cell adhesion molecules (CAMs) have been reported to be involved in the progression of atherosclerosis and plaque vulnerability. The aim of this study was to assess the association of adhesion molecule CD146 with carotid plaque instability.
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