Virulence of two Streptococcus pyogenes strains (types M1 and M3) associated with toxic-shock-like syndrome depends on an intact mry-like gene

Virulence of two Streptococcus pyogenes strains (types M1 and M3) associated with toxic-shock-like syndrome depends on an intact mry-like gene
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与中毒性休克样综合征相关的两种化脓性链球菌菌株(M1 和 M3 型)的毒力取决于完整的 mry 样基因

DOI:
10.1128/iai.61.12.5426-5430.1993
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发表时间:
1993
影响因子:
3.1
通讯作者:
J. R. Scott
J. R. Scott
中科院分区:
医学2区
文献类型:
--
作者:
J. Perez;H. F. Dillon;L. Husmann;B. Graham;J. R. Scott

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化脓性链球菌的主要毒力因子M蛋白在所研究的M 6型菌株中由mry在转录水平上正调控。我们在这里表明,在两个S。从中毒性休克样综合征病例中分离的化脓性链球菌菌株,M1型菌株和M3型菌株,也需要mry样基因来抵抗吞噬作用。
The major virulence factor of Streptococcus pyogenes, the M protein, is positively regulated at the transcriptional level by mry in the M type 6 strain studied. We show here that in two S. pyogenes strains isolated from cases of toxic-shock-like syndrome, a type M1 strain and a type M3 strain, an mry-like gene is also required for resistance to phagocytosis.
四种 A 组链球菌 M 蛋白基因前导序列的比较。
DOI: 10.1093/nar/16.10.4667
发表时间: 1988
影响因子: 14.9
作者:
Haanes-Fritz,E;Kraus,W;Burdett,V;Dale,JB;Beachey,EH;Cleary,P
通讯作者: Cleary,P
DOI: 10.1073/pnas.84.23.8677
发表时间: 1987-12-01
影响因子: 11.1
作者:
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通讯作者: SCOTT, JR
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