J wave syndromes: What's new?
J wave syndromes: What's new?
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DOI：
10.1016/j.tcm.2021.07.001
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发表时间：
2022-08
影响因子：
9.3
通讯作者：
Di Diego JM
中科院分区：
文献类型：
--
作者：
Antzelevitch C;Di Diego JM
Among the inherited ion channelopathies associated with potentially life-threatening ventricular arrhythmia syndromes in nominally structurally normal hearts are the J wave syndromes, which include the Brugada (BrS) and early repolarization (ERS) syndromes. These ion channelopathies are responsible for sudden cardiac death (SCD), most often in young adults in the third and fourth decade of life. Our principal goal in this review is to briefly outline the clinical characteristics, as well as the molecular, ionic, cellular, and genetic mechanisms underlying these primary electrical diseases that have challenged the cardiology community over the past two decades. In addition, we discuss our recently developed whole-heart experimental model of BrS, providing compelling evidence in support of the repolarization hypothesis for the BrS phenotype as well as novel findings demonstrating that voltage-gated sodium and transient outward current channels can modulate each other’s function via trafficking and gating mechanisms with implications for improved understanding of the genetics of both cardiac and neuronal syndromes.
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J波综合征专家共识会议报告：新兴概念和知识差距
影响因子：
2
作者：
Antzelevitch C;Yan GX;Ackerman MJ;Borggrefe M;Corrado D;Guo J;Gussak I;Hasdemir C;Horie M;Huikuri H;Ma C;Morita H;Nam GB;Sacher F;Shimizu W;Viskin S;Wilde AA
通讯作者：
Wilde AA
DOI：
10.1007/978-1-60761-161-5_3
发表时间：
2011-01-01
期刊：
MANAGEMENT OF CARDIAC ARRHYTHMIAS, SECOND EDITION
影响因子：
--
作者：
Antzelevitch, Charles;Yan, Gan-Xin
通讯作者：
Yan, Gan-Xin
影响因子：
4.2
作者：
Antzelevitch C;Patocskai B
通讯作者：
Patocskai B
影响因子：
5.5
作者：
Bastiaenen, Rachel;Hedley, Paula L.;Behr, Elijah R.
通讯作者：
Behr, Elijah R.
DOI：
10.1002/9780470994900.ch18
发表时间：
2005-01-01
期刊：
BRUGADA SYNDROME: FROM BENCH TO BEDSIDE
影响因子：
--
作者：
Belhassen, B;Viskin, S
通讯作者：
Viskin, S