Natural Herbal Medicine as a Treatment Strategy for Myocardial Infarction through the Regulation of Angiogenesis.

Natural Herbal Medicine as a Treatment Strategy for Myocardial Infarction through the Regulation of Angiogenesis.
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DOI:
10.1155/2022/8831750
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发表时间:
2022
期刊:
Evidence-based complementary and alternative medicine : eCAM
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其他
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我们对药用植物的生物活性成分及其对MI后血管生成的影响进行了文献检索。我们检索了2021年4月之前在Web of Science、MEDLINE、PubMed、Scopus、Google Scholar和中国国家知识基础设施数据库中的文章。 本文就铜离子、microRNA、Akt1、炎症反应、氧化应激、线粒体和周细胞参与心肌梗死后血管新生的机制进行综述。此外,我们还综述了丹参、红花等天然中草药的血管生成作用,葛根、黄芪、人参。梅,三七Chen,肉桂Cinnamomum sp.(L.)J. Presl,紫茎泽兰(Gaertn.)华盛顿特区,益母草,黄芩,和大叶水杨梅Geum macrophyllum Willd. 有些草药有促进血管新生的作用。在未来,天然促血管生成药物可能成为治疗心血管疾病的候选药物。
We conducted a literature search on the bioactive components of medicinal plants and their effects on angiogenesis after MI. We searched for articles in Web of Science, MEDLINE, PubMed, Scopus, Google Scholar, and China National Knowledge Infrastructure databases before April 2021. In this article, we summarized the mechanisms by which copper ions, microRNA, Akt1, inflammation, oxidative stress, mitochondria, and pericytes are involved in angiogenesis after myocardial infarction. In addition, we reviewed the angiogenic effects of natural herbal medicines such as Salvia miltiorrhiza Bunge Bunge, Carthamus tinctorius L., Pueraria lobata, Astragalus, Panax ginseng C.A. Mey., Panax notoginseng (Burkill) F.H. Chen, Cinnamomum cassia (L.) J. Presl, Rehmannia glutinosa (Gaertn.) DC., Leonurus japonicus Houtt, Scutellaria baicalensis Georgi., and Geum macrophyllum Willd. Some herbs have the effect of promoting angiogenesis. In the future, natural proangiogenic drugs may become candidates for the treatment of cardiovascular diseases.
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