Putting Glioblastoma in Its Place: IRF3 Inhibits Invasion.
Putting Glioblastoma in Its Place: IRF3 Inhibits Invasion.
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DOI:
10.1016/j.molmed.2017.07.008
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发表时间:
2017-09
影响因子:
13.6
通讯作者:
Holland EC
中科院分区:
文献类型:
--
作者:
Pattwell SS;Holland EC
With an unsurpassed capacity for invasion into normal brain tissue, glioblastoma multiforme is the most lethal primary brain tumor. New research suggests that altering a subset of extracellular matrix factors, including interferon regulatory factor 3 (IRF3) and casein kinase 2 (CK2), may decrease the migratory potential of these aggressive tumors.
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