Identifying and quantifying misclassified and under-reported AIDS deaths in Brazil: a retrospective analysis from 1985 to 2009.

Identifying and quantifying misclassified and under-reported AIDS deaths in Brazil: a retrospective analysis from 1985 to 2009.
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DOI:
10.1136/sextrans-2012-050632
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发表时间:
2012-12
影响因子:
3.6
通讯作者:
Pascom AR
Pascom AR
中科院分区:
医学2区
文献类型:
--
作者:
Fazito E;Cuchi P;Fat DM;Ghys PD;Pereira MG;Vasconcelos AM;Pascom AR

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对在巴西死亡率系统登记的死亡进行了回顾分析,以量化巴西15-49岁 人口中艾滋病毒/艾滋病死亡人数的漏报情况以及那些被错误归类为艾滋病相关疾病的死亡人数。1985-2009年艾滋病相关疾病的死亡率按年龄和性别计算。按年龄、性别分类的死亡率随时间的变化被用来确定可能被错误分类的艾滋病死亡情况,并量化相应的错误分类死亡人数。因不明原因造成的死亡被重新分配到所有其他自然死因中。根据死亡报告系统的不完整性,对由此得出的艾滋病死亡总人数作了进一步调整。在调查的28个潜在死因中,有5个以与艾滋病相同的独特年龄模式增加:肺炎、卡波西氏肉瘤、其他免疫缺陷、其他败血症和弓形虫病。从1985年到2009年,因这五种原因死亡的18490人被记录为艾滋病毒/艾滋病。38145例因不明原因造成的死亡被重新分配给艾滋病,并在艾滋病死亡人数上增加了15 485人,以纠正巴西死亡系统的完整性。在1985年至2009年期间,总共有72例 120人的死亡被记录为艾滋病,与该国报告的194例 445例艾滋病相关死亡人数相加,这意味着巴西对艾滋病死亡人数的错误分类占27%。这项研究表明,巴西官方死亡信息系统低估了艾滋病死亡率。今后需要努力减少对死因的错误分类,并确定如何保持死因信息的机密性。
A retrospective analysis of deaths registered in the Brazilian Mortality System was conducted to quantify the under-reporting of HIV/AIDS deaths and those misclassified to AIDS-related conditions in the 15–49 years old population in Brazil. Death rates for AIDS-related diseases were calculated by age and sex for 1985–2009. Changes in the age-sex-specific death rates over time were used to identify conditions likely to be misclassified AIDS deaths and to quantify the corresponding number of misclassified deaths. Deaths due to ill-defined causes were redistributed across all other natural causes of death. The resulting total number of AIDS deaths was further adjusted for incompleteness of the mortality reporting system. Out of the 28 potential causes of death investigated, five increased in the same distinct age pattern as AIDS: pneumonia, Kaposi's sarcoma, other immunodeficiencies, other septicaemia and toxoplasmosis. 18 490 deaths due to these five causes were recoded to HIV/AIDS from 1985 to 2009. 38 145 deaths due to ill-defined causes were redistributed to AIDS and 15 485 were added to the number of AIDS deaths to correct for completeness of the mortality system in Brazil. Altogether, 72 120 deaths were recoded to AIDS between 1985 and 2009 and added to the reported 194 445 AIDS related deaths in the country, representing 27% misclassification of AIDS deaths in Brazil. This study demonstrated that AIDS mortality is underestimated by the official mortality information system in Brazil. Efforts need to be made to reduce misclassification of causes of death in the future and identify ways in which the confidentiality of information regarding cause of death can be maintained.
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