Myocardial involvement in coronavirus disease 19.
Myocardial involvement in coronavirus disease 19.
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DOI：
10.1007/s00059-020-05001-2
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发表时间：
2020-12
期刊：
影响因子：
1.7
通讯作者：
Antz M
中科院分区：
文献类型：
--
作者：
Saleh A;Matsumori A;Abdelrazek S;Eltaweel S;Salous A;Neumann FJ;Antz M
2019年底，中国武汉一组病因不明的肺炎患者预示着2019冠状病毒病（COVID-19）的爆发。以前的严重急性呼吸系统综合征（SARS）乙型冠状病毒感染与心律失常和心力衰竭的体征和症状有关。引起COVID-19的SARS冠状病毒2 （SARS- cov -2）的出现迅速发展为大流行，大量感染患者报告有潜在的心血管疾病。由于关于病毒流行后心血管负担的公开数据很少，因此本研究旨在评估COVID-19对心脏的影响。这项前瞻性队列研究包括德国两个中心的40名成年住院患者。根据世界卫生组织（WHO）临时指南诊断为COVID-19的成年患者被纳入研究，重点关注SARS-CoV‑2对心脏的潜在影响。它基于实验室参数以及电和超声心动图值来确定SARS-CoV‑2病毒对心脏组织的影响。所进行的调查证实了急性心脏损伤与COVID-19之间的关系。COVID-19引起的心肌损伤和心肌功能受损很常见；然而，心脏实验室或超声心动图值与死亡率之间没有相关性。COVID-19感染后的心血管监测对于确定心脏受累负担至关重要。
In late 2019, a cohort of patients presenting with pneumonia of unclear etiology in Wuhan, China, heralded the outbreak of coronavirus disease 19 (COVID-19). Previous severe acute respiratory syndrome (SARS) beta-coronavirus infections have been associated with tachyarrhythmias and signs and symptoms of heart failure. The emergence of SARS coronavirus 2 (SARS-CoV-2), which causes COVID-19, has rapidly developed into a pandemic, and a large number of infected patients have been reported to have underlying cardiovascular disease. Since there are only scant published data regarding cardiovascular burden in the wake of viral epidemics, this study aimed to evaluate cardiac involvement in COVID-19. This prospective cohort study included 40 adult inpatients at two centers in Germany. Adult patients diagnosed with COVID-19 in accordance with World Health Organization (WHO) interim guidance were included in the study, which focused on the potential cardiac involvement of SARS-CoV‑2. It was based on laboratory parameters as well as electro- and echocardiographic values to determine the impact of SARS-CoV‑2 virus on heart tissues. The conducted investigations confirmed the relationship between the presence of acute cardiac injury and COVID-19. Myocardial injury and impaired myocardial function due to COVID-19 are common; however, no correlation was established between cardiac laboratory or echocardiographic values and mortality. Cardiovascular monitoring upon COVID-19 infection is crucial to determine the burden of cardiac involvement.
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影响因子：
5.4
作者：
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通讯作者：
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影响因子：
11.8
作者：
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通讯作者：
Schultheiss, HP
DOI：
10.1155/2012/351979
发表时间：
2012
期刊：
Influenza research and treatment
影响因子：
--
作者：
Ukimura A;Satomi H;Ooi Y;Kanzaki Y
通讯作者：
Kanzaki Y